Biomedical subjects

E Marshall

Publications and source records attributed to E Marshall.

At least 91 records · Page 5Linked to original sources

PubMed2000

Epidemiology. Duke study faults overuse of stimulants for children.

Some experts are growing concerned that Ritalin, a stimulant of the central nervous system used to calm a type of fidgety behavior called "attention-deficit hyperactivity disorder" (ADHD), is overused. Most psychiatrists think, however, that stimulants are being underprescribed, because too many cases of ADHD are going untreated. Now, an authoritative study published in this month's Journal of the American Academy of Child and Adolescent Psychiatry shows that Ritalin is being given to many children who don't fit the diagnosis of ADHD, while others who do are not receiving the drug.

Attention Deficit Disorder with Hyperactivity↗

PubMed2000

The shots heard 'round the world.

The massacre at Columbine High School last year unleashed a torrent of fresh concern over the threat that violence poses to society. It also energized a government research effort to understand and prevent violence. Ironically, this flurry of activity comes at a time when youth violence, as reflected in crime statistics, is in decline.

Aggression↗

PubMed2000

Bioterrorism. DOD retreats on plan for anthrax vaccine.

Anthrax bacterium, once the deadly scourge of goat-hair workers, has become the bane of the U.S. defense establishment. Without infecting a single soldier, it has created a logistical headache for the Pentagon, as military contractors have fallen far short of supplying a vaccine that will protect all troops and be acceptable to health authorities. Last week military officials were forced to beat a hasty retreat in their current efforts, raising the hackles of legislators who already had serious doubts about the program.

Anthrax↗

PubMed2000

Scientific publishing. Publish and perish in the Internet world.

When 120 leaders in publishing and biomedicine met here last week to talk about the Internet's effect on scholarly journals, it didn't take long for disagreements to surface. Participants clashed over two very different visions of the future--one predicting that private firms will continue to produce the most reliable and readable journals, the other that scientists will soon abandon traditional journals and share results directly with other researchers on the Internet.

Internet↗

PubMed2000

Human genome. Rival genome sequencers celebrate a milestone together.

At a White House ceremony on 26 June, two scientific groups, one funded by the government and the other privately funded, announced that they have generated a nearly complete readout of the 3.1 or so billion nucleotides in the human genome. The White House ceremony was more than a celebration; it was also designed to heal a split in the research community. The ceremony brought together leaders of the rival groups in a kind of truce, cooling off a competition that had grown intense in recent months.

Computational Biology↗

PubMed2000

Patent disputes. Biotech giants butt heads over cancer drug.

On 8 June, Chiron challenged Genentech's patent on an important new breast cancer drug called Herceptin and sued for a share of the profits. Chiron's 4-page complaint, filed in the federal district court in Sacramento, California, accuses Genentech of "willful, wanton, and deliberate" infringement of one of its patents. The case is being closely watched in the biotech industry not just because of the money at stake but also because it involves one of the first therapies to emerge from the burgeoning field of cancer genetics

Antibodies, Monoclonal↗

PubMed2000

Clinical trials. Harvard's Koski to lead human subjects office.

As Congress steps up oversight of human clinical trials, the Administration is getting a high-level manager of its own to watch out for the interests of volunteers in U.S.-financed research. As expected, Secretary of Health and Human Services (HHS) Donna Shalala last week named anesthesiologist E. Greg Koski, 50, to run a new HHS Office for Human Research Protections.

Administrative Personnel↗

PubMed2000