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E Marmo

Publications and source records attributed to E Marmo.

At least 271 records · Page 15Linked to original sources
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Effects of the intraperitoneal administration of diazepam on rat serum lipoproteins separated by polyacrylamide gel electrophoresis.

In normolipidaemic young rats the intraperitoneal administration of diazepam (10 mg/kg) induced a marked fall of the total serum lipids and total cholesterol. A dose of 5 mg/kg brought about an increase of HDL2 lipoprotein fraction and an elevation of the HDL2/HDL2.HDL3 ratio. Margarine administration elicited a significant augmentation of the total serum lipids and a reduction of the HDL2/HDL2.HDL3 ratio. The intraperitoneal injection of diazepam in margarine-treated rats brought about a decrease of total serum lipids and total cholesterol, (when compared to the margarine values), an obvious elevation of the HDL2 fraction and of HDL2/HDL2.HDL3 ratio. The LDL1 (beta) fraction was decreased. These data confirm our earlier findings which show that diazepam improves the HDL cholesterol/total cholesterol ratio.

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