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Biomedical subjects

E Markgraf

Publications and source records attributed to E Markgraf.

At least 37 records · Page 2Linked to original sources
PubMed1997

[Therapy of soft tissue injuries--biological strategies].

The traumatic soft tissue injury plays a central role in fracture healing. The knowledge of pathophysiological mechanisms has completely changed the management and therapy of injuries accompanied by soft tissue lesions. Treatment is aiming for prevention of the circle of hypoxia, microvascular perfusion disturbance, increased membrane permeability and potential infections. General therapeutic principles are decontamination, debridement, revascularisation and decompression. Modern methods of soft tissue treatment take these principles into consideration.

Debridement↗
PubMed1996

[Functional fracture treatment of the upper arm].

Using a functional brace, we treated 67 patients who had a fracture of the humeral shaft over a 5-year period from 1987 to 1992. We analysed several parameters of the fractures to discover those which influence healing. Desault, plaster cast or traction were used before applying a brace in an average time of 15 days. The osseous consolidation was 10 weeks in the average. The functional results were very good and good in 78.3%, acceptable in 18.3% and poor in 3.4% of the cases. Twelve humeral-shaft fractures were associated with a radial nerve palsy. Every patient recovered a full radial nerve function under the treatment with a functional brace. The retentive management of an operative treatment of humeral-shaft fractures associated with a nerve injury can be supported because of our experience.

Adult↗
PubMed1996

[Trauma in elderly patients].

The increasing proportion of old and very old people in the population has increased the task of treatment in the field of surgery and its main points. The decreasing function of and changes to the skeleton caused by osteoporosis have led to a number of fractures. The fracture near the hip joint is typical for this section of the population. 1180 patients from the Jena surgical clinic/casualty were analysed; the average age was over 75 years and the most common cause of accident was a fall. A quick operative treatment is recommended. In comparison with the risk factor of the ASA-classification 1.6% with factor I and 44.4% with factor IV died. Postoperative treatment is very important.

Accidental Falls↗
PubMed1995

[Indications for a new joint-bridging miniature external fixator in primary and secondary management of complex hand injuries].

25 patients with injuries of the hand were treated by a new external minifixator. A specific joint bridging construction makes it possible to treat severe joint fractures by ligamentotaxis. Another indication is the preoperative continuous elongation treatment in severe contractures of the fingers. The minifixator can be made dynamic and can also be used for interfragmental compression or distraction.

Adult↗
PubMed1993

[Amputation injuries of the upper extremity--early complications after replantation and revascularization].

Within a time of ten years 144 patients with difficult injuries on their hands were operated. These were 95 replantations and 102 revascularizations. 26 patients had to be operated again because of arterial and venous thrombosis. 46% of our patients had early vascular complications already within 24 hours. The frequency of thrombosis was increasing with the accompanying soft tissue injury and therefore with the gravity of the trauma. Avulsion injuries had of course the worst prognosis. After diagnosis of vascular occlusion within the replanted finger there should be a quick surgical revision of the anastomosis. With the help of application of urokinase into the artery we could create the circulation without any new production of the anastomosis in two cases. With a subtile technique of the disposition of the anastomosis and two venous connections to one artery with the replanted fingers we could reduce the rate of thrombosis and improve the results.

Adult↗
PubMed1989

[Traumatic vascular lesions of the knee joint].

The popliteal artery is a "critical" or key-artery, whose sudden occlusion leads to the ischemia-syndrome. The rate of amputation after missing or too late recovery is very high. The real time for the recovery runs to 3-6 hours. The reason for the injury of the vessel is the dorsal luxation of the knee-joint, the fracture of the lower thigh or the fracture of the tibial head with extreme dislocation of the fragments. The management of the diagnosis, the contents and the order of the surgical treatment are reported.

Amputation, Surgical↗
PubMed1986

[Primary tumors of the retroperitoneal space].

Symptoms, therapy, and prognosis of primary tumours of the peritoneum are reported in this paper, with reference being made to 86 malignant and 24 benign cases. The palpable tumour, impaired condition, and uncharacteristic abdominal pain were major symptoms. Intravenous urography and selective angiography, complementarily flanked and supported by computer tomography and sonography have proved to be important and valuable diagnostic methods. Only 23 per cent of malignant and 62 per cent of benign tumours were operable. Complete extirpation of the tumour was found to be the only promising therapy. Postoperative lethality after total extirpation amounted to ten per cent. Combination of surgical with radiotherapeutic approaches has proved to be favourable. The five-year survival rate accounted for 9.8 per cent or 44 per cent, following radical surgery.

Adolescent↗
PubMed1981

[Treatment of medial fractures of the femoral neck by prosthetic replacement of the femoral head].

At the Surgical University Clinic in Jena, between 1974 and 1978, an endoprothetic head of the femur was implanted in 92 patients with medial fractures of the femoral neck. 15% of these patients died within the first 3 weeks after the operation, 21% within the first year after the operation. 26 patients could be followed-up. In 21 of these patients the results were considered to be good or satisfactory. These results and the reports of other authors have shown, that under certain conditions discussed in this paper it is a good principle to perform an endoprothetic implantation of the head and of the femur in patients with medial fractures of the femoral neck.

Aged↗
PubMed1981

[The problem of documentation in traumatology].

An exact documentation is a necessary demand of modern medicine. Different methods of the registration of information, for example the conventional sick-paper, the punch card and the electronic data processing documentation are opposed with their pros and cons. The own experiences of the surgical hospital of the Friedrich-Schiller-University with the documentation of injured patients is shown and explained. The text points to the importance of the electronic data processing registration and evaluation of the many facts of the injured patients concerning the therapeutic, epicritical, but also epidemic and legal questions.

Accidents↗
PubMed1976

[Problem of catheter-embolism following subclavian puncture].

The catheterisation into the subclavian vein is important in the intensive therapy and for the prolonged parenteral nutrition. Numerous complications are described. In 300 catheterisations into the subclavian vein we observed 3 damages of catheters. The causes damages of catheters are investigated with the help of experiments. Recommendations to the prevention of the damage and the embolism of the subclavian catheters are given.

Adult↗