Biomedical subjects

E Manno

Publications and source records attributed to E Manno.

16 recordsLinked to original sources

PubMed2000

The hemostatic balance after plasma-exchange transfusion in myasthenia Gravis.

BACKGROUND: To study the effects of plasma-exchange on removal and recovery of haemostatic factors and inhibitors using albumin or PPS as replacement fluid. METHODS DESIGN: Prospective, noninterventional study. SETTING: Medical intensive care unit of a university hospital. PATIENTS: The study included 11 consecutive patients with Myasthenia Gravis, whose haemostatic parameters were normal before plasma-exchange. INTERVENTIONS: Plasma coagulative factors and inhibitors were studied before at the end of and 24 hours after each exchange. RESULTS: Immediately after exchange plasma coagulation factors and inhibitors evaluated were reduced, except for factor VIII; 24 hours later only fibrinogen was significantly decreased; D-Dimer was not found increased; the platelets, after exchange, were at normal levels. CONCLUSIONS: Our data show a parallel lowering of haemostatic factors and inhibitors after plasmapheresis using material devoid of coagulation factors as replacement, this explains the absence of hemorrhagic or thrombotic complications. So we think that careful monitoring of coagulation during plasma-exchange is not useful.

Hemostasis↗

PubMed1999

[Hyponatremia in neurosurgical patients].

Hyponatremia played an essential role in this case, determining the rapid transition from consciousness to a state of coma in female patient who had just come through the critical phase of intensive care. This circumstance underlines the importance of a correct water balance in patients undergoing neurosurgery, as well as a knowledge of the inappropriate antidiuretic hormone secretion (SIADH) syndrome responsible, either alone or in association, for the genesis of severe hyponatremia. In the differential diagnosis of hyponatremia, it is important to recall the role of an often mistaken syndrome (cerebral salt wasting syndrome) characterized by the secretion of a natriuretic factor that has still not been clearly identified.

Brain Injuries↗

PubMed1999

[Giromitra syndrome caused by false morel].

Three cases of mushrooms poisoning (by false morel) with associated gyromitra syndrome, due to a thermolabil toxin are reported. They showed a syndrome like to Amanita phalloides poisoning (gastroenteric symptomatology, diarrhoea) some hours after eating and then neurologic signs; they were hospitalized (without haemolytic signs) and were discharged from hospital a few days later in a good health.

Adult↗

PubMed1994

[Clinical nutrition in maxillofacial cancer surgery. A review of the literature].

The authors review the literature on problems of nutrition in patients with operable maxillofacial neoplasms. The causes of malnutrition in head-neck tumours will be particularly examined: metabolic alteration due to the presence of neoplasm; the tumour being situated in the first upper respiratory-digestive tracts; the side effects of chemotherapy and/or radiotherapy; the results of surgery and finally those of a late diagnosis. Once clinical nutrition has been indicated by both clinical and biochemical parameters, a plan for the most frequently used pre- postoperative treatments is drawn up. Reviewing the literature disagreement is found as the most effective method--enteral or parenteral--given that both solutions present advantages and disadvantages. The former is more physiological less expensive and simpler to carry out while the latter permits a more individualised form of treatment and the metabolic evaluation is simplified. The authors will go to present their own treatment plans: parenteral in the preoperative phase and in the postoperative patient a gradual weaning from parenteral to enteral treatment. The most important lines in both enteral and parenteral feeding are examined and the authors conclude by confirming that artificial nutritional therapy makes absolutely no difference to the prognosis but allows the patient to undergo the appropriate therapy.

Enteral Nutrition↗

PubMed1987