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Biomedical subjects

E Magee

Publications and source records attributed to E Magee.

5 recordsLinked to original sources

Effect of black tea drinking on blood lipids, blood pressure and aspects of bowel habit.

Thirty-one men (47 (SD 14) years) and thirty-four women (35 (SD 13) years) took part in a 4-week randomized cross-over trial to compare the effect of six mugs of black tea daily v. placebo (water, caffeine, milk and sugar) on blood lipids, bowel habit and blood pressure, measured during a run-in period and at the end of weeks 2, 3 and 4 of the test periods. Compliance was established by adding a known amount of p-aminobenzoic acid (PABA) to selected tea bags, and then measuring its excretion in urine. Mean serum cholesterol values during run-in, placebo and on tea drinking were 5.67 (SD 1.05), 5.76 (SD 1.11) and 5.69 (SD 1.09) mmol/l (P = 0.16). There were also no significant changes in diet, LDL-cholesterol, HDL-cholesterol, triacylglycerols, and blood pressure in the tea intervention period compared with placebo. Compared with placebo, stool consistency was softened with tea (P = 0.04), and no other differences were found in bowel habit. Results were unchanged when fifteen 'non-compliers', whose PABA excretion indicated that fewer than six tea bags had been used, were excluded from the analysis, and when differences between run-in and tea periods were considered separately for those who were given tea first or second.

4-Aminobenzoic Acid↗

A regression method for analysing ordinal data from intervention trials.

We consider the case of a community intervention trial evaluated with a series of cross-sectional surveys and having outcomes measured on an ordinal scale. We propose a modelling procedure that combines ridit analysis and linear regression methods. We use the multinomial distribution as the basis for variance estimation of the mean ridits and then use simple regression models to estimate differences (for example, between intervention and comparison areas) among the ridits. We illustrate this procedure with data from a community intervention trial promoting condom use, with the adoption of consistent condom use measured on a 5-point ordinal scale.

Clinical Trials as Topic↗

Predictors of bleach use among current African-American injecting drug users: a community study.

One hundred seventeen African-American current injecting drug users were interviewed in a closely matched pair of census tract communities in Dallas, Texas. A brief street intercept interview was administered that included an eligibility screener and questions on sexual behaviors with main or other partners and on injection drug paraphernalia bleaching behavior. Multiple regressions were conducted to determine significant predictors of frequency and duration of cleaning needles with bleach using different models (risk, attitude, exposure, and full). The variables measuring risk behaviors were age, frequency of sharing, exchanging sex for money, and sexual partner's use of injecting drugs. The predictors for the attitude model included normative, attitudinal, and self-efficacy items. The exposure to HIV information variables included seeing/hearing information; talking to someone about HIV, condoms, cleaning needles; and antibody testing for HIV. The full model combined predictors from each of the other models. Overall, bleach use is best explained in terms of specific attitudes rather than risk behaviors or information about HIV.

Adult↗

Views of mixed sex wards: a survey of patients, carers and nurses.

This paper describes the design and implementation of a survey carried out at Wharfedale General Hospital, related to the potential development of mixed sex wards. The survey of patients, carers and ward nurses, carried out in December 1992, demonstrated a general consensus of views on mixed sex ward options, and identified a number of key areas which need to be addressed before both sexes can be nursed satisfactorily on wards which have historically been used for males or females only. The recommendations arising from the survey are now being taken up by the hospital managers for further action.

Adult↗