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Biomedical subjects

E M Whelan

Publications and source records attributed to E M Whelan.

At least 19 recordsLinked to original sources
PubMed1995

The establishment of a genetic map of orf virus reveals a pattern of genomic organization that is highly conserved among divergent poxviruses.

The large differences between the G+C content of the orf virus genome and those of other characterized poxviruses have precluded the use of DNA hybridization to establish a gene map of orf virus. Here we have sequenced the ends of cloned restriction endonuclease fragments of the nZ2 strain of orf virus (OV) and used the translated sequences to search protein data bases. Sequence from 15 points found high-scoring matches to data base entries, including 18 vaccinia virus (VAC) genes. We also present 2 kb of sequence from a region near the right terminus of the OV genome and show that it encodes homologs of VAC genes, F9L and F10L. The data presented here in conjunction with published and as yet unpublished data have allowed the construction of a gene map of OV on which 37 genes have been placed. Thirty-two of these genes have homologs in VAC. Alignment of the OV gene map with that of VAC revealed that each OV gene and its VAC counterpart occurred in the same order and orientation on their respective genomes. The intervals between many of the points of sequence were also found to be strikingly similar. The conserved spacing of genes between OV and VAC within the central 88.2 kb of the 139-kb OV genome is not maintained in the termini where insertion, deletion, and translocation have occurred. Parallels are drawn between the data presented here and related data from swinepox virus and capripox virus.

Amino Acid Sequence↗
PubMed1995

Teenage smoking.

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Adolescent↗
PubMed1992

Health risks associated with excessive warnings about alleged cancer risks.

As the adage states, "when everything is dangerous, nothing is." If the word carcinogen (cancer-causing agent) is used to designate a spectrum of products, chemicals, and other environmental exposures, then the classification cancer causing when referring to the results of human epidemiological studies becomes meaningless. Thus, the emerging "carcinogen-of-the-week" phenomenon is counterproductive in preventing the toll of human cancer in that it diverts attention from real causes.

Attitude to Health↗
PubMed1990

Nutrition.

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Humans↗
PubMed1986

Promotion of tobacco products: issues and policy options.

During the past year, several prominent voluntary health organizations and professional medical associations have called for a ban on all forms of promotion of tobacco products. The proposal raises complex issues, ranging from determination of the effects of tobacco promotion to assessment of the constitutionality of banning advertising of a legal product. We identify the issues that underlie the concern of health professionals, review evidence addressing these issues, and describe and discuss frequently mentioned policy options, especially the ban proposal.

Advertising↗
PubMed1986

Public policy on smoking and health: toward a smoke-free generation by the year 2000. A statement of a working group to the Subcommittee on Smoking of the American Heart Association.

On May 20, 1984, the Surgeon General challenged the health community to work toward attainment of a smoke-free society by the year 2000. The leadership of the nation's three major voluntary organizations joined numerous associations of health professionals in accepting the challenge. The Subcommittee on Smoking of the American Heart Association (AHA) has concluded that attaining this objective requires the development and implementation of public policies designed to facilitate the transition from a smoking to a nonsmoking society. To study the relevant issues and recommend appropriate policies, the subcommittee commissioned a working group of distinguished experts in the field of smoking and health to prepare a policy statement. The statement, published here, has received the enthusiastic endorsement of the Subcommittee on Smoking and the leadership of the AHA. The working group discusses and recommends four policies: Increase the federal cigarette excise tax. Eliminate or restrict tobacco advertising and other forms of promotion. Assure the rights of nonsmokers to clean air through legislative means. Identify mechanisms to ease and assist the transition of tobacco farmers to other crops or careers.

Humans↗
PubMed1981

Cancer causation.

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Carcinogens↗
PubMed1980

Diet and hyperactivity: is there a relationship.

In 1973 Dr Ben Feingold, a California alergist, proposed that salicylates, artificial flavors, and artificial food colors are a cause of hyperactivity. Dr Feingold recommended a diet free of these substances as both treatment and prevention of the condition. He has published two popular books on the subject, Why Your Child Is Hyperactive (1974) and The Feingold Cookbook for Hyperactive Children (1979). Many parents have adopted the diet for their hyperactive children, and some have reported a noticeable improvement in their child's behavior when the diet was followed. In recent years a number of experiments have been carried out to evaluate the relationship between hyperactivity, salicylates, artificial flavors. The data indicate that the symptoms of the vast majority of cases of children labeled "hyperactive" are not related to additives in their diet.

Child↗
PubMed1975

Attitudes toward menstruation. International Committee on Applied Research in Population.

Historically, various interpretations of the menstrual process have been reflected in a wide, and usually negative, range of social attitudes toward menstruation. Recent clinical experience with continuation of the modern hormonal and mechanical methods of contraception that induce changes in the normal menstrual pattern suggests the need to understand current variations in attitudes and practices related to menstruation. This paper briefly outlines historical Western, Orthodox Jewish and Muslim, and contemporary US women's attitudes toward menstruation and begins to explore their relationship to contraceptive continuation.

Amenorrhea↗