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Biomedical subjects

E M Tsirul'nikov

Publications and source records attributed to E M Tsirul'nikov.

At least 19 recordsLinked to original sources

[The temperature-sensitive function of the skin mechanoreceptor endings].

Impulse activity of the ischiatic nerves single fibres in response to focused ultrasound stimulation of the rat hind-foot receptive fields, was studied. The receptor units were divided into low-, average- and high-threshold groups by the value of their threshold responses. No impulse activity was revealed in response to direct action of cold or warm water on the foot in the afferent fibres. Warm stimulation evoked most obvious changes in the low-threshold units, whereas latency noticeably changed in the average-threshold, and potential activity--in the high-threshold units rather. The data suggests involvement of the average-threshold units in the temperature perception.

Animals↗

[Focused ultrasound in research on somatic reception].

Focused ultrasound has been used to induce the following skin sensations: tactile and temperature ones; specific and unspecific pain, underskin or deep sensations: tactile sensations and some varieties of pain (muscle, periosteum and so on). It has been established that: somatic reception is attributed to mechanoreception; the same receptive structures are cold and warm ones; ultrasound has the sensibilized action. Sensation differences of corporal and auricular acupuncture points and some accidental skin underskin spots have been investigated.

Animals↗

[The pain sensitivity of the skin in chronic psychoemotional stress in man].

The focused ultrasound has been used for the comparative study of skin sensitivity to pain in 51 healthy men and 64 patients with neurasthenia, natural model of the chronic psycho-emotional stress. The patients showed a distinct tendency to a decrease of the pain threshold, lowered adaptation to the repeated threshold stimulus, sensitization. With the presence of the above-mentioned factors the pain syndrome occurred relatively more often. Taking into account the fact that the focused ultrasound of rather high intensity affects, first of all, C-afferents which are not only cutaneous but visceral nociceptors as well, an assumption is made that changes in pain sensitivity in the neurasthenic patients are not limited by skin but develop also in the inner medium forming the pain syndrome.

Adult↗

[Use of focused ultrasound in studying the tactile sensitivity of neurologic patients].

Tactile thresholds were measured with the focused ultrasound in 21 healthy subjects and 30 patients with various neurological diseases. All patients in spite of the level and origin of the disorder in the tactile--conducting pathways exhibited increased thresholds which were the most evident with 0.1--1 msec stimulus duration. This method allows not only to confirm the disorder of the tactile sensation, but to characterize it quantitatively including "subclinical" degree as well.

Adolescent↗