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Biomedical subjects

E M Scott

Publications and source records attributed to E M Scott.

At least 127 records · Page 7Linked to original sources
PubMed1977

Transport capacity, alkaline phosphatase activity and protein content of glutaraldehyde-treated cell forms of Escherichia coli.

Studies on the comparative transport capacity of various cell forms of Escherichia coli suggest that glutaraldehyde acts only in the outer regions of the cell envelope and to such an extent that transport of alpha-aminoisobutyric acid is reduced by 50%. Alkaline phosphatase activity in whole cells was severely impaired in the presence of alkaline glutaraldehyde and in NaCl-washed cells both acid and alkaline glutaraldehyde (0.01%) caused approximately 80-90% reduction in enzyme activity in 10 min. Protein content was reduced by only 10-15% with this concentration of glutaraldehyde, and cell volume decreased by the same extent. These results are discussed in terms of the mode of action of the disinfectant.

Aldehydes↗
PubMed1976

EPPS scores of male alcoholics: a review and cross-validation.

Mean EPPS scores for 20 male alcoholics at an outpatient clinic were found to be significantly higher than scores of Edwards' General Adult Sample of men on Heterosexuality, but significantly lower on Deference, Order, Affiliation, and Endurance. These differences are consistent with most prior research, but inconsistent with the earliest published study. Further research with the EPPS on alcoholic populations is encouraged.

Adult↗
PubMed1976

Acquisition and retention of habituation in the preweanling rat.

The acquisition and retention of habituation to air-puff was studied in rats on Days 1-19 postpartum. Animals of all ages demonstrated habituation but the rate of habituation varied with age: slower on each successive day from Day 1 to Day 8, but thereafter more rapid on each successive day. This peak of elicited responding is discussed in relation to the peak of spontaneous activity at Day 16 and to the pattern of neural development, including changes in acetylcholinesterase, norepinephrine, and serotonin, measured during the preweaning period. All ages showed 30-min retention of habituation, with 60-min retention developing after the 1st week. No evidence of 24-hr retention appeared at any age.

Acetylcholinesterase↗
PubMed1976

Stability of pseudorabies virus during freeze-drying and storage: effect of suspending media.

The effect of suspending media on the stability of pseudorabies virus upon freeze-drying and subsequent storage was studied. A variety of media was tested, including: sodium glutamate; sucrose; lactose; lactalbumin hydrolysate; peptone; a combination of sucrose, dextran, and glutamate; and various combinations of sucrose, glutamate, and potassium phosphates. Suspending media containing glutamate, either alone or in combination with sucrose and either dextran or phosphates, afforded the greatest degree of protection during the freeze-drying process and upon storage. Some possible functions of these additives in preventing injury to the virus during freezing and drying have been suggested.

Culture Media↗
PubMed1975

Atrial receptors and heart rate: the efferent pathway.

1. Stimulation of left atrial receptors by distension of the junctions between the pulmonary veins and the left atrium is known to cause a reflex increase in heart rate. It was suggested that the efferent path of this reflex was solely in the sympathetic nerves to the heart but more recently the existence of a vagal efferent component has been postulated by Albrook, Bennion & Ledsome (1972). 3. The junctions between the pulmonary veins and the levt atrium were distended before and after the administration of I.C.I. 66082 and bretylium tosylate. The response of an increase in heart rate was significantly decreased after the administration of I.C.I. 66082 (5 mg/kg) and abolished after the administration of bretylium tosylate (10 mg/kg). 3. It is concluded that the efferent pathway of the reflex is solely in the sympathetic nerves to the heart.

Animals↗