The history of cytogenetics. Portraits of some pioneers.
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Animals↗
Biomedical subjects
E M Rivera
Publications and source records attributed to E M Rivera.
Pain and immunologic response to root canal treatment and subsequent health outcomes.
OBJECTIVE: This study examined the effects of pain and stress associated with a dental procedure, root canal treatment (RCT), on natural killer cell cytotoxicity (NKCC) and the subsequent development of symptoms of upper respiratory illness during the following month. METHODS: Patients (N = 33) were recruited from those scheduled for RCT appointments. Subjects for a non-RCT comparison group (N = 14) were also recruited from dental clinic patients. Peripheral blood was drawn by use of an indwelling catheter three times: just before RCT, 30 minutes after injection of a local anesthetic, and 30 minutes after RCT (a parallel time course was followed for the comparison group.) Blood was assayed for cortisol and NKCC. Subjects completed a health diary in the month after RCT. RESULTS: Patients showed a significant increase in NKCC between baseline and RCT and a significant decrease from RCT to after RCT, whereas the comparison group did not. The NKCC following the RCT was negatively correlated with the pain level during RCT (r = -0.48, p < .01) and pain levels 2 and 6 hours after RCT (r = -0.43, p < .05; r = -0.44 p < .05, respectively). The patient group reported significantly more illness episodes 2 weeks after RCT than the comparison group (Wilcoxon rank sum = 4.78, p = .03). Discriminant function analysis correctly classified 88% of the subjects into the illness category using predictor variables of post-RCT NKCC, stress, and pain levels during RCT (F(3,21) = 8.23, p < .001). CONCLUSIONS: Transitory changes in NKCC associated with pain and stress may be implicated in the development of infectious disease episodes after an acute stressful event.
Adult↗
Considerations for the aesthetic restoration of endodontically treated anterior teeth following intracoronal bleaching.
The major considerations in restoring the pulp chamber following bleaching of endodontically treated anterior teeth include aesthetics, function, appropriate endodontic access preparation, amount of remaining tooth structure, type of restorative material, prevention of microleakage, and prevention of iatrogenic perforation. The learning objective of this article is to review the considerations that must be made when placing aesthetic restorations in the pulp chamber and access opening of endodontically treated teeth following intracoronal bleaching. The advantages and disadvantages of the proposed techniques and materials are discussed, as are the methods for avoiding excessive removal of the tooth structure. Two case reports are used to demonstrate the clinical procedures. The authors suggest placing white gutta-percha stopping material in the pulp chamber and a composite restoration in the access opening following root canal treatment and/or bleaching procedures in the anterior dentition.
Adolescent↗