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Biomedical subjects

E M Keating

Publications and source records attributed to E M Keating.

98 records · Page 6Linked to original sources

Comparison of intraoperative versus 24 hour antibiotic prophylaxis in total joint replacement. A controlled prospective study.

One hundred and ninety-six consecutive total joint recipients, including unilateral and bilateral procedures, were studied. Patients were randomly assigned to receive one of two prophylactic protocols. Group A (98 patients) received two intraoperative doses of cefuroxime (1500 mg and 750 mg) intravenously and continued cefuroxime for 24 hours postoperatively (750 mg every eight hours intravenous piggy back). Group B (98 patients) received two intraoperative intravenous doses of cefuroxime (1500 mg and 750 mg) and no postoperative doses. The opening or closing surgical culture was positive for five patients in Group A and 10 patients in Group B. None of these patients had a postoperative infection. Patients were followed for a minimum of one year after surgery. No deep wound infection was reported for either group.

Adolescent↗

Clinical, roentgenographic, and scintigraphic results after interruption of the superior lateral genicular artery during total knee arthroplasty.

Forty-eight patients treated by primary bilateral simultaneous total knee arthroplasty, in which one knee had a lateral release and the other did not, were evaluated clinically and roentgenographically from one to 12 years postoperatively. Thirty of these patients also had a technetium-99 bone scan. Mean clinical scores at the last follow-up examination were 90 for both groups. Roentgenographically, there were no subluxations, dislocations, or fractures in either group. There were two metal-backed patellae (one in each group) with signs of polyethylene wear and developed debris. Bone scans showed no difference between the two groups and no signs of osteonecrosis of the patella.

Aged↗

Posterior cruciate ligament balancing during total knee arthroplasty.

This study was undertaken to describe and evaluate the use of a posterior cruciate ligament balancing technique in total knee arthroplasty. Two hundred sixty total knee arthroplasties in 156 patients were performed between January 1984 and December 1985 using the described technique of posterior cruciate ligament balancing when necessary. Seventy-eight arthroplasties (30%) required ligament balancing to obtain a smooth flexion arc. At 1-year minimum follow-up evaluation, no knee was found to be unstable in the anterior-posterior plane. Average flexion arc for the posterior cruciate ligament balanced knees was 2 degrees - 114 degrees and for the standard arthroplasty was 2 degrees - 107 degrees. Posterior cruciate ligament balancing is a useful adjunct in total knee arthroplasty surgery when flexion gap tightness occurs.

Humans↗

Sagittal plane positioning of the femoral component in total knee arthroplasty.

The authors evaluated 623 total knee arthroplasties to determine the relationship between sagittal plane position of the femoral component and the final range of motion of the prosthetic knee. Two different prostheses were evaluated (Posterior Cruciate Condylar and A.G.C.) radiographically and functionally. Variation in sagittal plane position ranged from 20 degrees flexion to 20 degrees extension. No correlation between the sagittal plane position of the femoral component in either prosthesis and the final knee range of motion could be found. Sagittal plane femoral component position in the prostheses studied did not affect final range of motion when component position was between 20 degrees flexion and 20 degrees of extension.

Femur↗

Anterior femoral notching and ipsilateral supracondylar femur fracture in total knee arthroplasty.

The authors reviewed 670 total knee arthroplasties with a 2-10-year follow-up period. Of these, 180 knees had anterior femoral notching, which was deeper than 3 mm in 138. Two of the 670 knees suffered ipsilateral supracondylar fractures; one of these had a notched femur and one did not. Both fractures occurred at the anterior patellar flange-bone junction. No correlation was found between anterior femoral notching and ipsilateral supracondylar femur fracture.

Aged↗

Functional repair of rabbit gastrocnemius tendons using carbon fibers.

The ability of carbon fibers to form a secure anastomosis with soft tissue will have an important bearing on any future clinical uses. A secure anastomosis in rabbit Achilles tendons has been observed for up to 12 weeks after operation using a locking-weave suture, without immobilization. Impaired function occurred from slippage of the carbon fibers, which began by six weeks after operation, and which increased progressively at 13 and 42 weeks after operation. Satisfactory results were obtained using a modified Bunnell suture (with immobilization) in which the free ends of the carbon fibers were glued together with bone cement. In another study, carbon fibers that were weaved through intact rabbit Achilles tendons did not attach to the tendons during the postoperative time interval studied (18 weeks). It is possible, although difficult, to obtain a functional repair of the rabbit Achilles tendon using carbon fibers.

Animals↗

Patient controlled analgesia and GI dysfunction.

A prospective randomized study of 300 total joint replacement patients was done comparing the gastrointestinal (GI) side effects of morphine, meperidine, and nalbuphine given by patient controlled analgesia (PCA). All three groups of patients developed some form of GI dysfunction, but no significant difference was found among the three narcotics used. It was found that normal GI assessment in the initial postoperative period does not guarantee that GI function will remain normal. This finding indicates a need for extended nursing assessment of the GI status of the postoperative PCA patient.

Analgesia↗

The influence of age and gender on the outcome of total knee arthroplasty.

1. The influence of age and gender on the outcome of total knee arthroplasty was examined in 762 knees (490 patients). 2. Gender was shown not to significantly affect the outcome of total knee arthroplasty. Age was observed to produce a significant difference. 3. These results confirm the clinical expectation that both male and female older patients can expect equally favorable outcomes following total knee arthroplasty.

Adult↗