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Biomedical subjects

E M Innes

Publications and source records attributed to E M Innes.

12 recordsLinked to original sources

A quality assurance model for multidivision clinical departments.

Structuring a workable quality assurance (QA) program for multidivision and multispecialty clinical departments presents a considerable challenge. The Medical Center of the University of California, San Francisco (UCSF) found that QA activities in such departments were best handled by a committee of department physicians assisted by a QA staff person. This article provides examples of how two departments at the UCSF medical center structured QA committees to fit their departments' individual needs and explains how these committees fit in the medical center's overall QA program.

Hospital Bed Capacity, 500 and over

Leucocyte function in a case of chronic benign neutropenia of infancy associated with circulating leucoagglutinins.

A case of chronic benign neutropenia is described in association with circulating leucoagglutinins. IgG and IgM leucoagglutinins demonstrated by Sephadex G-200 chromatography agglutinated neutrophils and monocyte enriched leucocyte preparations. Total IgG, IgA, IgM and IgE, total haemolytic complement, C3 and C4 complement components were all within normal limits. Lymphocyte populations and transformation were normal apart from a relative increase in the number of B lymphocytes. In vitro studies showed that the patient's monocytes responded in chemotaxis, phagocytosis and intracellular killing of S. aureus in a comparable fashion to that of control neutrophils. Although the patient's serum also agglutinated monocytes these findings do not exclude the possibility that leucoagglutinins may have aetiological significance in this disease. The study also emphasizes the versatility of the monocyte in benign neutropenia.

Agglutinins