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Biomedical subjects

E M Bricker

Publications and source records attributed to E M Bricker.

33 records · Page 2Linked to original sources

Current status of urinary diversion.

The need for urinary diversion is widespread for both benign and malignant disease and for patient of all ages. In the past 25 years, the urinary conduit concept of diversion has been the most widely practiced modality and has produced results that have been gratifying and acceptance, though not perfect. It is doubtful that a "perfect" solution to bladder substitution will ever be found, i.e., a solution without complications and without risk to long-term renal function. Of the various conduit operations, ileal conduit has been the one most widely employed. This procedure has produced a lower incidence of pyelonephritis and hyperchloremic acidosis than any method of diversion prior to 1950. However, it has been associated with significant complications and a threat to long-term renal function is now being recognized. Various efforts at improving these results are under way, aimed chiefly at avoiding the effects of ureteral anastomosis to irradiated bowel and at the development of non-refluxing ureteral anastomoses. Only time and careful study will determine the results of these efforts. We should adopt standardized parameters in the next 25 years in order to make meaningful comparisons possible. The parameters of greatest importance are a definition of complications clearly resulting from the diversion, a definition of pyelonephritis, and an agreement on a standard definition of "renal deterioration".

Adult↗

Repair of postirradiation rectovaginal fistula and stricture.

Postirradiation rectovaginal fistulas are notoriously difficult to repair, as are the strictures that are usually associated with them. Previous attempts have involved resection and low anastomosis by various techniques. Patients considered not suitable for resection have been treated by permanent fecal diversion. A technique of repair not previously reported has been described. It relies on the proximal part of the colon as a vascular pedicle graft, used as a patch to close the rectal defect and to provide circumference to relieve any associated stricture. Five patients are reported in whom complicated fistulas and strictures have been corrected with restoration of normal rectal function.

Aged↗

The evolution of the ileal segment bladder substitution operation.

The historical background and events leading to the development of ileal conduit bladder substitution are reviewed. The reported results of twenty-five years experience with the operation are discussed with special reference to the early and long-term complications and risk to renal function. The importance of continued efforts to minimize these risks, especially when the operation is done in children and for benign disease, is emphasized. It is suggested that some of the more promising variations in the operation should be set up as prospective studies in order that meaningful comparisons may be possible in the future.

Adult↗