Search PubMed⌕ Search

Biomedical subjects

E Lukaschek

Publications and source records attributed to E Lukaschek.

5 recordsLinked to original sources

[Radiologic changes in the bones of the hand in progressive scleroderma].

27 patients suffering from progressive systemic sclerosis on both hands were examined through x-ray in two levels. The findings have been evaluated with regard to eight diagnostic criterions and then related to clinical and laboratory data. The results allow the differentiation between two groups of patients: group A revealing obvious radiological and laboratory evidence of inflammation and severe symptoms as well as a relatively short duration of the disease; group B showing fewer inflammatory signs with less developed symptoms and a significantly longer duration of the disease. The clinical and prognostic significance of these two different courses of PSS is discussed with special reference to overlapping syndromes of connective tissue diseases or subclasses of PSS.

Adolescent↗

Altered cellular immunity in Werner's syndrome.

A cellular immunodeficiency was revealed in a 39-year-old female patient suffering from Werner's syndrome. Relevant findings were negative intracutaneous tests to candidin, trichophytin, tuberculin and bacterial antigens, reduced lymphocyte response to PHA, and impaired intracellular killing of Candida albicans by granulocytes. The inclination of patients suffering from Werner's syndrome to develop neoplasms may be related to this immunodeficiency.

Adult↗

Disorder of cellular immunity in pemphigus vegetans.

In an untreated 26-year-old female patient suffering from Neumann's pemphigus vegetans for 8 months (with neither preceding thymoma nor myasthenia gravis), several in vivo and in vitro phenomena of immunodeficiency involving both T and B cell system were disclosed. A diagnosis of defective immune state was established on the basis of the low IgG-serum level (though pemphigus antibodies were present), reduced T cell count in blood, weak PHA stimulation of lymphocytes, lack of skin reactivity to recall antigens and to most other bacterial antigens tested. Impaired chemotaxis and a deficient intracellular killing of Candida albicans by PMNL were also found. The conclusion is drawn that a combined disorder of both the B and T cell system is involved in the etiology of pemphigus vegetans, even when thymoma is ruled out.

Adult↗

[Sarcoidosis].

Explore the source record for details and available documents.

Adrenal Cortex Hormones↗