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Biomedical subjects

E Luczywek

Publications and source records attributed to E Luczywek.

32 records · Page 2Linked to original sources

[Cerebral functional asymmetry in face perception by the patients with focal brain damage].

The results are reported of the study of face perception in a group of 18 healthy subjects and 10 patients with lesions in the right or left cerebral hemisphere. The task given to these subjects included identification of a face photograph exposed for 20 msec in the right or left field of vision. The index of perception coefficient was the number of errors made while addressing the material to the left or right cerebral hemisphere. The results of the experiment confirmed the hypothesis of the dominant role of the right hemisphere for face perception. The results suggest also that face perception disturbances occur without respect to the site of lesion in the right hemisphere.

Brain Injuries↗

[The process of learning verbal material in patients with various damaged cerebral structures].

The results are described of a study of the process of verbal material learning and its recall after distraction in 20 patients with involuntary movements treated by thalamotomy, and in 20 epileptic patients treated by amygdalotomy and hippocampotomy. In both groups learning difficulties had been noted already before the operation. In postoperative tests these difficulties were found to have increased immediately after the surgical intervention in patients with lesions in the left cerebral hemisphere. On the other hand, late after the operation they were particularly pronounced after lesions placed in the right thalamus. Disturbances of material recall after distraction were shown in both groups independently of the side of the lesion.

Adult↗

[Verbal, visual and aural memory in the early postoperative period in patients treated by thalamotomy].

Verbal memory and learning ability were determined before the operation and immediately 3-4 weeks after stereotactic surgery in 11 patients with extrapyramidal motor disturbances treated by ventrolateral (VL and Vim) thalamotomy. Preoperative examinations demonstrated disturbances of short-term verbal memory with narrowing of its extent and increased susceptibility of the trace to interference. Long-term memory was disturbed also, with presence of difficulties in recall and difficulties in memorization of verbal materials. Directly after the operation, in relation to the preoperative testing, increased disturbances were demonstrated in all stages of verbal memory, after damage to the border area of VL and Vim nuclei in the left as well as in the right thalamus. It was possible to detect some functional differentiation between thalamic lesions, with a tendency for increased disturbances of short-term verbal visual memory after right-sided thalamotomy and verbal auditory memory after left-sided thalamotomy.

Adult↗

[Effect of amygdalotomy on behavior disorders in epileptics].

Results of psychological testing in 46 epileptics with severe behaviour disturbances treated surgically, by the stereotaxic method (selective exclusion of the dorso medial parts of amygdalae) are reported. After the operation there was a significant improvement of behaviour and seizures of temporal-lobe type were no longer observed. Comparative tests demonstrated a significant reduction of emotional tension, development of ability to behaviour and emotional reactions control, reduction of emotional instability and motor hyperactivity. Aggressiveness in difficult or conflict situations was markedly diminished or eliminated.

Adolescent↗

[Processes of verbal memory in patients with involuntary movements treated by thalamotomy].

The authors tested verbal memory and learning in 15 patients with motor disturbances treated by ventrolateral thalamotomy before operation and late after it, after a mean time of 5.8 years. Disturbances of verbal memory in the form of retrieval of information from the memory stores and disturbances of learning of verbal material were found already before the operation. In comparative investigations late after the operation greater disturbances of verbal memory were observed with disturbances of verbal retrieval from memory stores after damage to the VL nucleus in the left as well as right thalamus. On the other hand, no decrease of the mental efficiency of these patients was demonstrated.

Follow-Up Studies↗

[Temporal lobe epilepsy during the growth stage treated by amygdalotomy and hippocampotomy].

The authors describe the results of stereotaxis treatment of epileptic patients with behaviour disturbances in developmental age. The indications to surgical treatment were established on the basis of stereo-EEG investigations. For the analysis 20 patients were selected and divided into two groups depending on the state of mental efficiency. Surgical treatment included selective amygdalotomy and hippocampotomy in different variants. The analysis of this material showed that the clinical improvement was greatest in patients with short period of epilepsy duration and with IQ above 90. This suggests that patients with temporal lobe epilepsy with behaviour disturbances in developmental age should be referred for stereo-EEG investions and stereotactic treatment possibly early.

Adolescent↗

[Changes of cognitive and emotional processes during immunostimulatory treatment in subacute sclerosing panencephalitis].

In 35 cases of SSPE sensibilized neuropsychological testing was done before and after 6 months of immunostimulatory and virostatic treatment. Three groups of patients were studied. All groups received isoprinosine, one group was given additionally TFX-thymus extract Polfa, and another group received additionally Propionibacterium granulosum KP-45. A tendency for improvement of verbal function and emotional status was observed only in the group receiving isoprinosine with propionibacterium. In both remaining groups, receiving only isoprinosine or isoprinosine with TFX worsening was noted, particularly in the isoprinosine-only group. This was particularly evident in the visuospatial orientation. Prolongation of survival time in SSPE owing to specific treatment increases the need for psychoreactive and therapeutic influences for stimulation of cognitive processes.

Adolescent↗

[Cerebral blood changes during neuropsychological tests administered by Doppler sonography. Preliminary report].

The preliminary studies on cerebral blood flow changes during neuropsychologic tests were carried out using transcranial Doppler sonography (TCD). The procedure with the standardized cerebral activation in order to obtain the control brain activity level was elaborated and tested. Blood flow velocity changes were measured during two groups of tests: linguistic with left dominant hemisphere and visual-spatial with right dominant hemisphere. Similar dynamics of blood flow changes was observed with all kinds of brain activation with the maximum velocity increase of 15-20%. The velocity measured in the dominant hemisphere was about 8-10% above the contralateral side. TCD seems to be complementary to the neuropsychologic tests useful especially in diagnosis of different types of dementia.

Brain↗

[Effect od amygdalectomy on memory and learning in patients treated surgically for epilepsy].

The results of neuropsychological investigations of 40 patients with severe epilepsy and behaviour disturbances treated by stereotactic methods are presented. In all cases memory disturbances were found before the operation, in 45% of the cases mental sluggishness was present. After amygdalotomy, together with a reduction of emotional tension and psychomotor agitation, the range of direct memory extended and difficulties in learning verbal material decreased. In some patients a tendency was observed also for a rise in intelligence quotient.

Adolescent↗

[The effect of stereotaxic injuries on the medial temporal brain structures on memorization of successively or simultaneously presented material].

Effect of stereotaxic injuries to the medial temporal brain structures on memorization of material presented successively or simultaneously was studied. The study aimed at testing whether stereotaxic damage to the hippocampus and amygdala results in a memory deficit and whether functions subserved by those structures depend on type and organization of the memorized material. The results indicate that even small damage to the medial temporal lobe structures may result in a deficit in memorization ability. The greatest impairment was observed for successive presentation of nonverbal stimuli.

Adult↗

[Evaluation of perceptive activity in persons with low pressure hydrocephalus treated surgically. Preliminary report].

Preliminary assessment of perceptive activity was carried out in patients with low-pressure hydrocephalus diagnosed clinically. The purpose of the study was establishing of the valuable tests for the neuropsychological diagnosis making possible finding of perceptive processes most frequently disturbed in low-pressure hydrocephalus. The studied group comprised 53 patients operated on for this hydrocephalus. In only 9 cases the condition of the patient made possible a detailed study of the perceptive processes. In this group the tests were carried out three times: before, immediately and after a longer time after insertion of ventriculoperitoneal shunt. The results showed differences in the level of general perceptive functioning in the whole group. In the subgroup studied in detail no general perception deterioration was found, and the usual disturbances were noted in the memorization of new information and in visuospatial orientation. Late after the operation the greatest improvement was observed in the most disturbed functions.

Adult↗

[Multi-stage method for the diagnosis of low-pressure hydrocephalus].

Multistage method of low-pressure hydrocephalus diagnosis, elaborated in our department, is discussed. The method consists of four stages: I Clinical and neuropsychological examinations, standard computerized tomography. II Somatosensory evoked potentials. III Determination of water concentration and distribution in fluid compartments of the brain by utilising new mathematical formula. IV Three-phase complementary test. The application of this method allows to eliminate many false diagnoses and may contribute to lower costs of treatment.

Body Fluid Compartments↗