Biomedical subjects

E Loh

Publications and source records attributed to E Loh.

93 records · Page 6Linked to original sources

PubMedDate not supplied

Ranking of facial profiles among Asians.

The purpose of this study was to determine the facial profile preferences in a sample of 1,189 Asian teenagers (aged 15.3 +/- 3.2 years). Five facial profile types were computer-generated by trained personnel (orthodontists and oral maxillofacial surgeons) to represent distinct facial types. Subjects were asked to rank the profiles in descending order of attractiveness. The ranking was as follows: orthognathic profile, bimaxillary retrusive profile, bimaxillary protrusive profile, mandibular retrognathic profile, and mandibular prognathic profile. The differences in rank scores between all the profile types were statistically significant (p < 0.05). Assessment of profile types among lay personnel could provide clinicians an indication into the relative attractiveness among profile types and health care workers in treatment prioritization among dysmorphic facial types.

Adolescent↗

PubMedDate not supplied

Report of the consensus conference on candidate selection for Heart Transplantation-1993.

BACKGROUND: Despite several task forces and numerous reviews, criteria for candidate selection for heart transplantation are not uniform. METHODS AND RESULTS: This report summarizes results compiled from a survey that was reviewed at a consensus conference held before the meeting of the International Society of Heart and Lung Transplantation in 1993 in Boca Raton, Florida. The meeting was attended by representatives of 52 programs from the United States, Canada, England, and Australia. The unique feature of this report is that is represents a review of the actual practice of patient selection at some of the largest and most experienced centers in the field. Key areas of the selection process including medical and surgical alternatives to transplantation, the composition of the transplant work-up, specific inclusion criteria as well as specific psychosocial factors and specific disease etiologies and co-morbidities that might represent contraindications were extensively reviewed. In addition, the standard follow-up for a patient on an active waiting list, and criteria to remove patients from the active waiting list are described. This survey provides information and insight regarding current areas of consensus as well as disagreement regarding candidate selection for heart transplantation. CONCLUSIONS: These differences may be important when considering outcomes and possible strategies in the use of resources.

Data Collection↗

PubMedDate not supplied

Role of panel-reactive antibody cross-reactivity in predicting survival after orthotopic heart transplantation.

To test the hypothesis that elevated preformed circulating antibody levels, as measured by panel-reactive antibody levels, predict survival after orthotopic heart transplantation, we analyzed 120 consecutive patients undergoing heart transplantation at the Brigham and Women's Hospital in a retrospective, chart-review format. Prospective, donor-specific lymphocyte crossmatches were performed in all patients with a panel-reactive antibody level of 10% or greater. Both the peak pretransplantation panel-reactive antibody level and the panel-reactive antibody level obtained on the day of transplantation were analyzed with respect to the end points of the number of acute rejection episodes, presence of coronary artery disease, and overall survival after transplantation. Patients with a panel-reactive antibody level on the day of transplantation of 25% or greater, despite a negative prospective donor-specific lymphocyte crossmatch, demonstrated a trend toward reduced actuarial long-term survival compared with patients with panel-reactive antibody values less than 25% (p < 0.05). Panel-reactive antibody levels were not predictive of the number of acute rejection episodes, early (< 60 days) versus late (> or = 60 days) death, or the development of graft coronary artery disease. No episodes of hyperacute rejection were observed, even in six patients with a positive retrospective donor-specific lymphocyte crossmatch. In conclusion, an elevated panel-reactive antibody value of 25% or greater at the time of heart transplantation may be a risk factor for decreased long-term survival. A trend toward an increased risk of death caused by rejection was also observed.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗