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Biomedical subjects

E Leonard

Publications and source records attributed to E Leonard.

13 recordsLinked to original sources

Outpatient transurethral resection of the prostate at a urological ambulatory surgery center.

Transurethral resection of the prostate has been the standard treatment for patients with benign prostatic hyperplasia, and it has traditionally required 2 to 7 days of hospitalization. Since 1991 we performed outpatient transurethral resection of the prostate at a urological ambulatory surgery center on 125 select patients. Standard resection techniques were used with particular attention to hemostasis, since bladder irrigation was stopped before patients were discharged home. Transfer to a hospital was required for 3 patients because of hematuria, 1 for fever and suspected bacteremia, and 1 for cardiac dysrhythmia. No patient required hospitalization after he was discharged from the ambulatory surgery center. Outpatient transurethral resection of the prostate can be performed safely with excellent patient satisfaction and cost-effectiveness. Alternative treatment modalities for benign prostatic hyperplasia should be evaluated against outpatient transurethral resection of the prostate before they are broadly embraced.

Adult↗

Reliability of a functional mobility assessment tool with application to neurologically impaired patients: a preliminary report.

The purpose of this preliminary study was to examine the intratester and intertester reliability of a functional mobility assessment tool (FMAT). Seven licensed physical therapists with varying amounts of clinical experience served as raters. Twelve patients with neurological deficits were subjects for this study. Raters were asked to provide eight possible ratings for each of eight critical mobility functions. Average weighted kappa coefficients ranged from .82 to .97. Intraclass correlation coefficients ranged from .73 to .97 for the first assessment and from .52 to .97 for the second (retest) assessment. A high degree of agreement between and within seven raters indicated that this tool may provide an effective assessment of stroke, brain injury, and spinal cord injury. Preliminary findings indicate the functional mobility assessment tool is reliable, thereby increasing the usefulness of this method for clinical assessment. The high resolution of the FMAT makes this tool ideally suited for use in future studies focusing on the prediction of mobility function following neurological insult.

Activities of Daily Living↗

A computerized kinematic diagnostic system.

This paper describes the instrumentation developed for a clinical system that measures upper extremity kinematics in normal and cerebral palsied children. The ability to diagnose cerebral palsy during early and midinfancy is influenced by the fact that movement and postural abnormalities become apparent only over time, and are not readily detectable until there is sufficient abnormality so that it can be viewed by gross inspection during clinical examination. The methodology presented here serves to discriminate normal from deviant movement at an earlier age than what is presently possible, and may also result in alternative therapeutic intervention.

Biomechanical Phenomena↗

Lymphocytes and lymphokines in aplastic anemia: pathogenic role and implications for pathogenesis.

Clinical observations first suggested an immune basis for aplastic anemia. Laboratory studies have implicated a suppressor T lymphocyte producing molecules like gamma-interferon that inhibit hematopoiesis. Extrapolation from in vitro studies is complicated by synergy and antagonism among lymphokines and interleukins, the presence of regulators of proliferation produced by bone marrow cells, and possible differences between endogenous and exogenously administered molecules on cell growth.

Anemia, Aplastic↗

Teaching car passenger safety to preschool children.

An educational curriculum entitled "Bucklebear" was designed to increase safety seat and seat belt use in young children enrolled in preschool programs (day care centers and nursery schools). Three basic concepts were emphasized: (1) "buckling up" is a good habit for everyone for every ride; (2) the back seat is the best seat; and (3) there are desirable passenger behaviors. The curriculum included training workshops with teachers, parent meetings, classroom lessons, sound filmstrip, puppet play, and many other activities. Six experimental programs and seven control programs with 402 and 427 enrolled children, respectively, participated. After their participation in the educational curriculum, children in the experimental program increased their use of a safety seat or seat belt from 21.9% to 44.3%. These children also increased their knowledge and simulated practice of car passenger safety.

Accident Prevention↗