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Biomedical subjects

E Leiter

Publications and source records attributed to E Leiter.

At least 55 records · Page 3Linked to original sources
PubMed1981

Interstitial irradiation of carcinoma of the prostate with 125iodine and simultaneous extraperitoneal pelvic lymphadenectomy in 32 patients: trials, tribulations and possible triumphs.

A series of 32 patients with carcinoma of the prostate who underwent 125iodine interstitial irradiation to the prostate and simultaneous extraperitoneal pelvic lymphadenectomy was reviewed. The patients were segregated into 3 groups: group 1-patients with early localized low grade disease, group 2-patients with advanced localized high grade disease and group 3-patients with early localized high grade disease and those with advanced localized low grade disease. Owing to the high degree of predictability of the absence or presence of pelvic lymph node metastasis in patients in groups 1 and 2 and the morbidity associated with superficial pelvic lymphadenectomy we do not advocate this procedure in these patients. However, we advocate pelvic lymphadenectomy in patients in group 3 because of the unpredictability of lymph node metastasis. Furthermore, our data indicate that 1) the morbidity of the combined procedures is relatively low, with no patients becoming incontinent and only 12.5 per cent becoming impotent, 2) 125iodine interstitial irradiation of the prostate after transurethral prostatectomy is safer in terms of postoperative complications than is radical prostatectomy and 3) while superficial pelvic lymphadenectomy is not an innocuous procedure it generally is safe and, at times, an important diagnostic staging procedure.

Adenocarcinoma↗
PubMed1981

Genital abnormalities and abnormal semen analyses in male patients exposed to diethylstilbestrol in utero.

Urologic examination of 48 male patients exposed in utero to diethylstilbestrol showed genital abnormalities in 29. Only 33 per cent of the patients studied had normal semen analyses by Eliasson scoring. Genital abnormalities demonstrated included varicoceles, epididymal cysts, hypoplastic testes and undescended testes among others. None of the patients had elevations of alpha-fetoprotein or beta-subunit human chorionic gonadotropin. The high incidence of the aforementioned abnormalities suggests that all male patients exposed to diethylstilbestrol should undergo urologic examination and semen analysis. Additionally, a history of diethylstilbestrol exposure should be sought in all patients with apparent idiopathic infertility.

Abnormalities, Drug-Induced↗
PubMed1981

The influence of neonatal orchiopexy upon the testis in persistent Müllerian duct syndrome.

We report on a patient with persistent müllerian duct syndrome and normal external genitalia who had embryonal cancer of the testis 16 years after neonatal bilateral orchiopexy. In previous cases the testes of these patients have not been considered predisposed to form tumors. However, the occurrence of a testis tumor has been reported in 8 patients with this syndrome. The specific factors resulting in tumor formation in such patients are uncertain. Until they are clarified we suggest that these patients should be observed carefully for the possible development of testis tumor.

Adolescent↗
PubMed1981

Associated anomalies of mullerian and wolffian duct structures.

Over a ten-year period, we identified 457 patients with renal or uterine anomalies. Only 12 of 55 patients with anomalies of mullerian development had an intravenous pyelogram, which revealed an associated renal anomaly in five. Conversely, only two of 21 women with renal anomalies had a gynecologic evaluation; one of them had a bicornuate uterus. Although the association between anomalies of mullerian and wolffian development has been known for some time, the appropriate studies to demonstrate such an association are not routinely done in clinical practice. All female patients with congenital renal anomalies of size, position, or number should have either ultrasonography (in children) or hysterosalpingography (in adults). All patients with congenital uterine or vaginal anomalies should have an intravenous pyelogram.

Abnormalities, Multiple↗
PubMed1980

Invasion of the rectum by carcinoma of the prostate.

Denonvillier's fascia ordinarily serves as an effective barrier to the posterior extension of carcinoma of the prostate. Consequently, it is generally unappreciated that cancer of the prostate can invade the rectum posteriorly and appear at diagnosis to be a rectal mass. Autopsy series show that this occurs in from 0.56% to 11.5% of all cases of prostatic carcinoma. When it does appear as a rectal mass, it can be confused with carcinoma of the rectum. Unless a biopsy confirms rectal carcinoma, such an error may even result in an inappropriate abdominoperineal resection of the rectum. Every surgeon must be aware of this entity, its presumed pathogenesis, and its three clinical types: rectal ulcer, stricture, and anterior rectal mass.

Aged↗
PubMed1980

Laparoscopy as a diagnostic aid in women with localized ureteral obstruction due to endometriosis.

Endometriosis is a common disease which can produce localized ureteral obstruction. Many women will have significant disease without any clinical signs or symptoms until they present with distal ureteral obstruction. In the reported literature, the diagnosis of ureteral involvement by endometriosis usually has been made at surgery. It is therefore suggested that women with distal ureteral obstruction not attributable to calculous disease undergo laparoscopy in an attempt to rule out endometriosis as the cause of ureteral obstruction.

Adult↗
PubMed1980

Renal failure in diabetes after intravenous urography.

A review of the literature reveals that patients with juvenile onset diabetes with azotemia, associated vascular disease, and proteinuria, are at great risk of sustaining acute renal failure following intravenous pyelography. Predisposing factors are identified, but the exact mechanism of acute renal failure remains obscure. Since no prophylactic measures or effective treatment exist, the benefits and risk must be weighed prior to the procedure.

Acute Kidney Injury↗
PubMed1980

Ureaplasma urealyticum (T-mycoplasma) infection: does it have a role in male infertility?

Ureplasma urealyticum (T-mycoplasma) has been related to male infertility by some observers. To assess further this question 150 couples who presented for fertility had semen and cervical mucus cultures for mycoplasma. Positive cultures were obtained from 69 couples. There were no significant differences in the semen analyses among patients with positive or negative cultures. The presence of mycoplasma in the semen is probably the result of contamination at the time of ejaculation. Routine investigation for the presence of mycoplasma in subfertile men is unjustified. The routine use of broad-spectrum antibiotics in subfertile patients with positive mycoplasma culture is unnecessary.

Cervix Mucus↗
PubMed1980

Lobulated inverted papilloma of the ureter.

An inverted papilloma of the ureter with ipsilateral hydronephrosis was found in a 77-year-old man who had a history of prostatic carcinoma. Inverted papilloma of the urothelium is a rare lesion, with the vast majority of cases being found in the bladder. To date none has been documented in the ureter.

Aged↗
PubMed1980

Importance of collateral circulation of bowel in urologic surgery.

As urologic surgery becomes more extensive planned or inadvertent compromise of the vascular supply of the bowel becomes more likely. Familiarity with the normal anatomy of the vascular supply of the large and small intestines must, therefore, be part of every urologist's fund of knowledge. With an appreciation of the critical areas of collateral circulation conclusions can be drawn as to which arteries can and cannot be ligated safely. Intraoperative Doppler flow studies may help the surgeon to evaluate whether collateral supply is adequate to maintain bowel viability. In certain marginal situations hydration and postoperative treatment with antibiotics may be helpful.

Aged↗
PubMed1979

Persistent fetal ureter.

Six patients have been seen with a peculiar ureteral lesion that has not been described previously. The lesion is characterized by either local segmentation or convolution and may represent either a persistent fetal ureter or a form of ureteral dysgenesis. Proximal dilatation, when present, has been less than the original radiographic appearance of high grade obstruction would lead one to expect. The ureteral lesions have disappeared progressively, suggesting that a period of conservative observation is warranted in similar situations.

Female↗
PubMed1978

Bilateral herniation of renal pelves: a complication of cutaneous pyelostomy.

The first reported case of bilateral herniations of the renal pelves as a complication of cutaneous pyelostomy is presented. We describe a modification of the original surgical technique that may prevent herniation, based on fixation of the pelvis to the lumbodorsal fascia as well as the cut edge of the pelvis to the skin. In our patient the bilateral herniations were corrected by repairing the fascial defects and suturing of the pelvis to the fascia.

Chromosomes, Human, 6-12 and X↗