An atypical eating disorder following cancer chemotherapy.
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Biomedical subjects
Publications and source records attributed to E Leibenluft.
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The author interviewed staff on three psychiatric wards to elicit their response to pregnant colleagues. Staff expressed particular concern about protecting the pregnant women from possible patient assaults. Some staff members were overprotective or unwilling to express anger directly toward the pregnant staff members. Staff also reported increases in jealousy, maternal transference and countertransference, anxiety about the impending separation, flirting with the pregnant women, and joking about sex. The author compares these findings with reports from outpatient settings and discusses potential implications.
While a subset of depressed patients are believed to "self-medicate" their depression with alcohol, there are no studies comparing the phenomenological and diagnostic characteristics of patients with primary depression and secondary alcoholism with those of patients with depression or alcoholism alone. In this study, we compared 11 patients from each of these three diagnostic groups in terms of past history and current clinical presentation. The patients were matched for age, sex, and level of function. Comorbid patients were most likely to meet criteria for sedative dependence and panic disorder, and had higher scores on the Hamilton Anxiety Scale. In addition, they scored higher on a hypomania scale and had more first-degree relatives with a history of drug abuse.
While a number of studies demonstrate that gonadal steroids regulate circadian rhythms in animals, the issue has received little attention in humans. The question is relevant to our understanding of gender differences in the phenomenology of depression, and of changes in the sleep-activity cycle that are seen in affective illness and during the menopause. In this paper, the literature demonstrating that gonadal steroids regulate circadian rhythms in animals is reviewed, along with the limited human literature. A hypothesis is forwarded suggesting that, in humans, estrogen shortens the circadian period, lengthens the sleep phase, advances sleep onset, and consolidates sleep. A study in progress is described which is designed to test the effects of the hypogonadal state, estrogen, and progesterone on circadian rhythms in women.