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Biomedical subjects

E Latta

Publications and source records attributed to E Latta.

11 recordsLinked to original sources
PubMed1993

Preceptor workshops: a collaborative model.

Educational programs for nurses are becoming increasingly reliant on clinicians in hospitals and other health care agencies to act as preceptors for their students. Often there is no formal preparation for this role, nor are rewards provided by the educational institutions. This paper describes a collaborative effort between a university and a college program to prepare and reward nurses who work as preceptors with students in their settings.

Education, Nursing, Baccalaureate↗
PubMed1983

[Activity of the creatine kinase isoenzyme CK-BB in the serum of neonates as an indicator of perinatal damage to the central nervous system].

By means of the immunoprecipitation method significantly higher activities of creatine kinase BB isoenzyme were measured in the sera of neonates with CNS symptoms than in the sera of healthy or sick neonates without CNS symptoms. The activity of CK-BB inversely correlated with the one-minute Apgar score. These results suggest a leakage of CK-BB from the damaged CNS tissue into the blood circulation. Determination of CK-BB might be helpful in the assessment of perinatal brain damage.

Apgar Score↗
PubMed1983

Penetration of the colon by a ventriculo-peritoneal drain resulting in an intra-cerebral abscess.

A male child was born with internal hydrocephalus due to aqueductal stenosis requiring a ventriculo-peritoneal shunt on the first postnatal day. Subsequently, the hydrocephalus did not subside but increased. Autopsy at the age of 15 months disclosed the peritoneal tip of the catheter located inside the transverse colon, the cerebral tip of the catheter within a huge abscess of the right cerebral hemisphere. Penetration of the intestine by a ventriculo-peritoneal catheter seems to be a rare event, occasionally resulting in early death due ascending infection.

Brain↗
PubMed1980

[Prenatal diagnosis of alpha-1-antitrypsin phenotype. Case record and prognosis in severe alpha-antitrypsin deficiency Pi ZZ (author's transl)].

A mother had a child with cirrhosis of the liver and alpha-1-antitrypsin deficiency. In a subsequent pregnancy the fetal phenotype Pi MZ was detected by isoelectrofocusing in the amniotic fluid. Quantitative assay of alpha-1-antitrypsin gave results in the normal range. Umbilical vein blood analysis confirmed the antenatal findings. In this case it has been possible to rule out the disease before birth. In this context the clinical importance of alpha-1-antitrypsin deficiency is stressed, its frequency in the European and North-American population and the prognosis with phenotype Pi Z.

Female↗
PubMed1976

[Tuberous sclerosis with megalocornea and coloboma of the iris (author's transl)].

A mentally and physically retarded 4 1/2 year-old boy with epileptic seizures showed a megalocornea on both sides, a coloboma of the iris in the right eye and a white area at the temporal side of the disc in the left eye. At first a coloboma of the disc was suspected. By further controls at the age of 8 years a typical two diopters elevated nodular opaque white mass was seen in place of the white area in the left eye, in addition two flat tumours were also seen. In the right eye with coloboma of the iris there was also a flat area. Radiographically the right kidney showed two ureters with flat calyces. At the age of 8 years symmetrical face naevi occurred only under atropine medication, and showed at the age of 10 years the typical picture of Pringle's tumours.

Abnormalities, Multiple↗
PubMedDate not supplied

[Possibilities for false-negative findings in trisomy 21 screening with FISH].

In approximately 5% of individuals with Down syndrome aneuploidy results from a chromosomal rearrangement. FISH analysis on chromosome metaphases and interphase nuclei of 5 individuals with Down syndrome carrying different types of chromosome 21 translocations demonstrated the diagnostic efficiency of this method. By use of different commercially available chromosome 21 specific probes we were able to show that only the cosmid probe specific for the Down syndrome critical region (DCR) in 22qll gave reliable results for interphase analysis of trisomy 21, while the use of chromosome 21 centromere- or of painting probes carry a high risk of a false-negative diagnosis in translocation trisomy 21.

Aneuploidy↗