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Biomedical subjects

E Larson

Publications and source records attributed to E Larson.

At least 163 records · Page 9Linked to original sources

Assessing the quality of care for urinary tract infection in office practice: a comparative organizational study.

As part of a comprehensive evaluation of care received by enrollees in a prepaid community health care project, we studied the process of care for enrollees reported to have a urinary tract infection. The care given to 98 patients enrolled in a large prepaid group practice (PGP) and 69 patients seen by 45 physicians in the independent practice setting (IPP) was analyzed. We found the process of care to be significantly better in the PGP, with a large part of the difference due to more appropriate utilization of urine cultures. This occurred despite a higher visit rate to internists in the IPP, and suggests that the organization of practice strongly affects the process of care received by patients even when all care is fully prepaid.

Ambulatory Care

The epidemiology of Staphylococcus aureus in a newborn nursery from 1970 through 1976.

Results of seven years of epidemiologic surveillance for Staphylococcus aureus in a newborn nursery are presented as a follow-up of a study from this same institution published in 1969. Surveillance of the previous study included years 1961 through 1968. A continued rise in S. aureus colonization rates among newborns occurred from 1973 through 1976 as compared to previous years studied. This was related primarily to the discontinuance of hexachlorophene (HCP) bathing. Other contributing factors were the addition in 1972 of the umbilical (as well as anterior nares) site for culturing, potentially doubling the S. aureus retrieval; the use, beginning in 1972, of an HCP-inhibiting medium for staphylococcal culturing; and probably the presence in previous years of the Hawthorne effect. Clinical infection rates with S. aureus also increased significantly (P less than .001)when HCP bathing was in abeyance. Antibiotic sensitivity patterns of S. aureus isolated from 1970 through 1976 have remained the same. Five phage types were recurrent in causing clinical infections throughout the seven years. A recommended program for control of staphylococcal disease in the newborn nursery includes concentration on improvement of each staff member's individual technique, continuous epidemiologic surveillance, and routine umbilical care with triple dye or bacitracin. Bathing of infants with HCP should be considered a temporary treatment to be terminated as acute disease is controlled.

Cross Infection

E trisomy phenotype associated with small metacentric chromosome and a familial Y-22 translocation.

As a result of this case report, several entities are postulated due to an extra metacentric D or E chromosome: 1) infants presenting with a phenotype similar to the E 18 trisomy; however, the karyotype can be interpreted as either a deleted E or D chromosome; 2) another group of children all presenting with mental retardation, facial asymmetry, scoliosis and cerebral palsy, postulated due to a partial trisomy of E 16 or E 17; 3) individuals with a normal phenotype, but chromosomally presented with an additional satellited metacentric chromosome consistent with centric fusion of a D or G chromosome and 4) children presenting with an inconsistent phenotype and chromosomally presenting with an extra chromosome manifesting satellites or satellite association; the same chromosome abnormality often is found in unaffected parents and/or sibs.

Chromosome Aberrations