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Biomedical subjects

E Lale-Murix

Publications and source records attributed to E Lale-Murix.

6 recordsLinked to original sources
PubMed1997

A case-control study on lymphocytic subsets in elderly bearing a gastroenteric cancer.

The aim of this work is to evaluate the differences in lymphocytic sub-classes between elderly patients with gastroenteric cancer and elderly patients with a non neoplastic disease. A group of 88 patients over 60, consecutively admitted to the III Division General Surgery for gastro-enteric cancer has been collected for the study, the control group consisted of 74 patients also over 60, consecutively admitted over the same period for benign abdominal diseases. In all patients the following data were measured: body mass index (BMI), white blood cells (WBC), total lymphocytes, total T lymphocytes (CD3+), helper T lymphocytes (CD4+), suppressor T lymphocytes (CD8+), CD4+/CD8+ ratio, B lymphocytes, CD5+ B lymphocytes, activated T lymphocytes (CD3+ HLA-DR+), CD4+ "naive" lymphocytes (CD4+ CD45 RA+), CD4+ "memory" lymphocytes (CD4+ CD45 RO+), NK lymphocytes (CD16+ 56+), red blood cells (RBC), total serum cholesterol, albumin, total serum proteins. The main lymphocytic subsets were on an average lower in the cancerous elderly group with respect to the non cancerous. As the tumour progressively increases in size (T), total lymphocytes significantly decrease, while CD4+ progressively decreases with nodal involvement (N). In the cancerous elderly, we found a lower immune response. The immune system appears to be less efficient also in association with tumor growth, especially when T and N get worse. The response of effector cells to the tumour seems not specific.

Aged↗
PubMed1995

Giant sigmoid diverticulum.

The case of a giant diverticulum of the sigmoid colon in a 74 year-old woman is reported. The diverticulum had perforated into the urinary bladder and required a 3-phase operation with resection of the sigmoid colon and urinary bladder. Giant diverticulum is considered a rare complication of diverticulosis. Generally, it is a pseudo-diverticulum that grows due to a valve mechanism working in the neck of the diverticulum. The differential diagnosis lies mainly between intestinal duplication and pneumatosis cystoides. Surgical therapy yields favorable results.

Aged↗
PubMed1994

[Modified Gilbert's technique in the treatment of persistent inguino-scrotal hernias in aged patients].

In elderly males, and in particular in very old men, the anatomical changes produced by senility encourage the formation of large inguino-scrotal hernias. Their repair may be achieved using Gilbert's technique to which the authors have proposed a number of variants. The good results show that the "tension-free" technique may be correctly applied in elderly patients with inguino-scrotal hernias, thus allowing a straightforward postoperative recovery with no complications.

Age Factors↗
PubMed1991

[Immunological variations after thymic stimulation with special reference to IL2-RS in patients operated for neoplasms].

The paper reports a study which was carried out to assess immunological function by assaying IL2 in cancer-operated patients treated with thymostimulin. The results of the study show that, used in normally fed, immunodepressed patients, this immunomodulator is able to normalise levels of lymphocyte subpopulations and to bring serum concentrations of IL2-RS to the levels of normoergic patients.

Adjuvants, Immunologic↗
PubMedDate not supplied

[External saphenous vein excision with mini-phlebectomy].

The surgical treatment of the varicosities of the short saphenous vein is one of most controversial matter of modern phlebology. The anatomy of this vessel, that is deep, and is accompanied by the sapheno external nerve, can be very varied species for that which concerns the sapheno popliteal joint. The traditional surgery as the sclerotherapy exposes the patient to risks and failures. For such reasons the authors believe that the modern technique of stab evulsion phlebectomy could be formatted like the treatment of choice of the venous pathology of the short saphenous vein. Synthesizing, the stab evulsion phlebectomy consists of the removal of the varicosities of the lower limbs through incisions of the skin of 1-3 mm using special surgical instruments with hook (Chrochets). The technique doesn't foresee neither stitching neither vascular binding, and could be performed on local anesthesia and in ambulatory regimen. The results of the technique and the absence of complications suggests its adoption of principle in the treatment of the incompetence of the short saphenous vein.

Humans↗