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Biomedical subjects

E Lahat

Publications and source records attributed to E Lahat.

At least 91 records · Page 5Linked to original sources

Elevated serum creatine kinase. Following febrile seizures.

Serum creatine kinase (CK) was determined in 52 children admitted following an episode of febrile convulsions. Enzyme levels correlated with the estimated duration of the seizure. Twenty-four hour values were significantly higher than those observed 1 hour after the convulsive episode. Serum CK levels are frequently used for diagnostic purposes, so the questionable validity of this test when drawn after a convulsive episode must be considered.

Age Factors↗

Chorea associated with systemic lupus erythematosus in children. A case report.

In the past most cases of childhood chorea were related to rheumatic fever and were treated appropriately. With the decrease in the incidence of rheumatic fever less common etiologies of chorea should be investigated. This report demonstrates the difficulties of distinguishing between chorea associated with rheumatic fever and chorea associated with systemic lupus erythematosus.

Child↗

Peripheral facial nerve paralysis in children: the value of routine diagnostic work-up studies.

Acute facial nerve paralysis is a relatively common pediatric disorder. Idiopathic facial nerve palsy (Bell's palsy) has to be distinguished from other etiologies. Retrospective review of the results of routine diagnostic work-up studies of our patients, failed to reveal any clinically significant abnormalities and did not provide more data as far as etiology or indication for management. Significant history and positive findings on physical examination should direct the physician towards specific diagnostic procedures.

Adolescent↗

Transient aphasic episodes due to hypoglycemia.

A 58-year-old diabetic man suffered two episodes of hypoglycemia accompanied by isolated aphasia. Prompt resolution of the language disorder followed treatment with 50% glucose IV. The day following the first event the EEG demonstrated bitemporal delta activity, more prominent over the left hemisphere. EEG repeated two weeks after the second event showed residual left temporal slowing. The differential diagnosis between hypoglycemia and transient ischemic attacks in diabetic patients presenting with transient focal neurological deficit is emphasized.

Anomia↗

Dermoids of the posterior fossa. Case reports and review.

Three children are presented with dermoid cysts of the posterior fossa, one of the most common locations of dermoid. They were initially diagnosed as having abscesses. Clinical presentations included hydrocephalus and recurrent meningitis. A helpful clue for identification is a bony defect of the skull on plain film or on a bone-window at Computed Tomography (CT).

Abscess↗

Vaccine-associated contact paralytic poliomyelitis with atypical neurological presentation.

Paralytic poliomyelitis presenting with quadriparesis, transient encephalitis and bulbar symptoms in 2 patients in close contact with recently vaccinated children with trivalent live oral polio vaccine is described. Symmetrical lower motor neuron involvement of deltoid muscles with electromyographic confirmation was found. Upper motor neuron signs, with symmetrical hyperactive deep tendon reflexes developed in the lower extremities. Poliovirus Type-2 vaccine-like strain was cultured from one patient and both patients showed significant antibody titers rises to poliovirus. Attention is drawn to the possible clinical differences between vaccine associated poliomelitis and the usual features found in wild strain poliomyelitis. It is suggested that in selected cases, non-immunized contacts be given inactivated polio-vaccine when the vaccinees are immunized with the live oral-vaccine.

Adult↗

Schwannoma presenting as lumbar disc disease in an adolescent boy.

Lumbar disc disease and spinal cord tumors occur relatively rarely in the pediatric age group. We report on a 16-year-old boy who presented with signs and symptoms of lumbar disc disease that failed to respond to conservative treatment. He was diagnosed preoperatively to have schwannoma of the S-1 root.

Adolescent↗

Recurrent abdominal and cervical pains. An unusual clinical presentation of acute rheumatic fever.

Most cases of acute rheumatic fever (ARF) present with arthritis, carditis or choreiform movements. However, a variety of clinical manifestations which are not included in the modified Jones criteria can be the presenting symptoms of the disease. We describe a case of a 10-year-old boy with ARF who presented with recurrent episodes of abdominal and cervical pain who later developed an active carditis which established the diagnosis of ARF. A high degree of suspicion and an awareness of the less common manifestations of ARF are necessary to make an early diagnosis and initiate appropriate treatment in certain cases of ARF.

Abdomen↗

Shigellosis: incidence of convulsions and resistance to antibiotics.

One hundred and ninety-three children with bacillary dysentery were admitted to the "Assaf Harofeh Hospital" during the years 1975-1980. Generalized convulsions were observed in 37 (19.2%) children. The incidence of seizures was significantly higher in children whose age ranged between 1 and 6 years when compared to those below or above this age range. Convulsions were not observed when fever was below 38 degrees C, however, higher fever was not associated with a parallel increase in their incidence. Temperature above 38 degrees C was less common in infants compared to older children. These findings suggest that convulsions in shigellosis do not differ from simple febrile convulsions in respect to age, sex, presence and degree of fever. The incidence of resistance to either ampicillin or trimethoprim-sulfamethoxazole was similar in all the various shigella strains isolated in our population.

Age Factors↗

Acute appendicitis in early childhood.

1728 appendectomies were performed in our institution between the years 1973 and 1978, only 18 of them below the age of 5 years. Acute appendicitis in this age is characterized by a very low incidence (1%); an overwhelming male predominance (8:1), a short history, and a rapid progress of the disease. In 72% perforation of appendix and peritonitis were present at operation. The triad of fever, abdominal pains and vomiting was present in all cases. A high leucocyte count was noted in all cases except one. All patients were operated upon within 16 h of admission. No mortality, a low morbidity and a short hospital stay were recorded.

Acute Disease↗