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Biomedical subjects

E L Derlacki

Publications and source records attributed to E L Derlacki.

At least 19 recordsLinked to original sources
PubMed1988

Binaural hearing after middle ear surgery. Masking-level difference for interaural time and amplitude cues.

Previous investigations have shown that binaural hearing is often abnormal in patients having conductive hearing losses, and even in patients who have had hearing thresholds corrected by middle ear surgery. The present study assessed further the masking-level difference (MLD) in patients who had previously undergone middle ear surgery. The stimuli were chosen such that the sensitivity to interaural time difference cues and to interaural amplitude difference cues could be assessed independently. Results indicated that the MLD is abnormal in more than a third of 15 patients, even after surgery has restored normal hearing at the frequency of the test. The MLD is more likely to be reduced for the cue of interaural time difference than for interaural amplitude difference. Subjects who had lesions of long duration, early onset, and large asymmetry were particularly likely to have reduced MLDs.

Adolescent↗
PubMed1985

Revision stapes surgery: problems with some solutions.

A review of 217 consecutive revision stapes operations performed during a ten-year period revealed that the surgeon encounters more pathological variables than he does during primary operations. Hence, the technical solutions are less stereotyped and the net results less predictable. Prosthesis displacement, with or without incus tip erosion, was the most common primary cause of failure (82%). However, oval window problems such as footplate refixation, perilymph fistula, otosclerotic regrowth, and lateralized oval window membrane in 60% of cases often complicated prosthesis displacement. First revision operations in 174 cases resulted in postoperative bone-air deficit of 10 dB or less in 65% of cases, much better than the 45% for second revision results, and the 25% for third revisions. These statistics provide our practice with a realistic prognosis when discussing revision stapes surgery with the individual surgical candidate.

Bone Conduction↗
PubMed1985

The versatility of presculptured homograft incus prostheses.

A twelve-year experience with banked homograft ossicles has developed into a system of presculptured incus allografts adapted for the correction of many ossicular defects encountered in tympanoplasty and revision stapes surgery. The standardized preparation of a number of variations of modeled incus prostheses for an operating room bank by a well-trained ear homograft laboratory technician has been an effective and time-saving technique.

Ear Ossicles↗
PubMed1976

Adenomatous tumors of the middle ear and mastoid.

Three cases of middle ear and mastoid neoplasms are reported as "adenomatous tumors" since in their search of the literature the authors did not find any previously described lesions with a similar histologic appearance and benign biologic behavior. Microscopically, all three tumors are similarly composed of solid cords and nests of closely-packed small cells having an epithelial appearance. Two distinct cell types are present: cuboidal cells, arranged in a rudimentary gland-like pattern, and angular cells forming irregular nests with no distinct pattern. All three tumors developed in patients in their 20's, over a period of months with minimal symptoms; yet in all of the lesions the tympanic membrane was intact at the time of initial examination. None of the neoplasms was diagnosed preoperatively, and, once removed, all three tumors were pathologic enigmas and therapeutic problems in view of the initial and subsequent consultant pathologic opinions; nevertheless, total local excision with preservation of the tympanic membrane would appear to be safe treatment in these cases. The term "adenomatous tumor" is applied to these three neoplasms because: 1. a true glandular epithelial origin warranting the term adenoma or adenocarcinoma cannot be proven; and 2. the biologic behavior and prognosis is not necessarily reflected by the histologic appearance. A more specific term reflecting the origin and behavior of these tumors does not appear possible without the study of further cases.

Adenocarcinoma↗