Isoleucyl-tRNA synthetase. A fluorescence study of the binding properties of the synthetase from Escherichia coli.
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Biomedical subjects
Publications and source records attributed to E L Bennett.
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Wet weight of rat cerebral cortex was increased by exposure to an enriched environment, as compared with standard colony or impoverished conditions. Dry weights and wet weights were compared and both yielded identical percentage differences between brains of animals experiencing enrichment and those experiencing impoverishment.
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The opioid peptide dynorphin(1-13) impairs memory formation in chicks (5). We examined whether this occurs for both aversively and appetitively motivated learning. Four-day-old chicks were injected with dynorphin(1-13) into the intermediate medial hyperstriatum ventrale and trained on either a peck avoidance (PA) or an appetitive discrimination (AD) task; 2-day-old chicks were trained on PA. In 2-day-old chicks, dynorphin was amnestic for PA at 0.01, 0.03, or 0.1 mM. In 4-day-old chicks, dynorphin impaired memory formation for PA at 0.1 mM, and for AD training at 0.03 mM. Thus, similar doses of dynorphin impair memory formation for both appetitive and aversive conditioning.