[Radioisotope renographic studies on children with obstruction of the urinary flow in the upper urinary tract].
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Child↗
Biomedical subjects
E Kun
Publications and source records attributed to E Kun.
Mode of action of the antibiotic X-537A on mitochondrial glutamate oxidation.
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Adenosine Diphosphate↗
Paediatric isotope-renographic observations in upper urinary tract obstruction.
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Adolescent↗
Growth hormone secretion in children during corticosteroid treatment. Responses to arginine.
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Adolescent↗
Inhibition of the oxidation of glutamate and isocitrate in liver mitochondria at a specific NADP+-reducing site.
The cation-complexing carboxylic-acid antibiotic X-537A, at concentrations far below that required for ionophorous activity, selectively inhibits the oxidation of glutamate and isocitrate by liver mitochondria in steady-state 3. The site of inhibition has been localized specifically at the reduction of NADP(+). Glutamate and isocitrate dehydrogenases, the oxidation of NAD(+)-dependent substrates, pyridine nucleotide transhydrogenations, and the respiratory chain between NADH (or NADPH) and O(2) are unaffected by the antibiotic X-537A. Kinetic evidence, i.e., competition between chlorotetracycline (a fluorescence probe for membrane-bound bivalent cation) and X-537A, indicates that the NADP(+)-reducing, antibiotic-sensitive site is most probably associated with the inner mitochondrial membrane.
Adenosine Diphosphate↗
Hypoglycaemia in infants and children with cyanotic congenital heart disease.
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Adolescent↗
Platelet adhesiveness in cyanotic cogenital heart disease.
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Adolescent↗
Rate-limiting steps of gluconeogenesis in liver cells as determined with the aid of fluoro-dicarboxylic acids.
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Animals↗
Inactivation of the tricarboxylate carrier of liver mitochondria by (-)-erythrofluorocitrate.
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Animals↗
The oxidation of L-lactate by liver mitochondria.
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Acetoacetates↗
Studies with specific enzyme inhibitors. XIV. The effects of enzymatically synthesized (-)-erythro-fluoromalic acid on malate dehydrogenase and on anion carriers of liver mitochondria.
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Animals↗
Prevention of Ca(2+) induced cation efflux from liver mitochondria by a cytoplasmic factor and by oligomycin.
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Journal Article↗
[Diagnosis of recurrent abdominal pain in children].
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Abdomen↗
Control of cation movements in liver mitochondria by a cytoplasmic factor.
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Animals↗
Separation and characterization of aconitate hydratase isoenzymes from pig tissues.
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Animals↗
Gas chromatographic separation of esters of fluoro analogs of citric acid cycle intermediates.
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Acids↗
Studies with specific enzyme inhibitors. 13. Kinetics of nonenzymatic decarboxylation of fluorooxalacetic acid.
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Catalysis↗
Fluorocitrate inhibition of aconitase: relative configuration of inhibitory isomer by x-ray crystallography.
The fluorocitrate isomer that is a strong inhibitor and inactivator of aconitase has been shown by x-ray crystallographic studies on the rubidium ammonium salt to have the configurations (1R : 2R) or (1S : 2S) 1-fluoro-2-hydroxy-1,2,3-propanetricarboxylic acid. A possible mechanism for the action of fluorocitrate is proposed which involves the 1R : 2R isomer suggested from biochemical data.
Citrates↗