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Biomedical subjects

E Kollin

Publications and source records attributed to E Kollin.

At least 37 records · Page 2Linked to original sources

[Postcholecystectomy syndrome: endoscopic and radiological aspects (author's transl)].

542 patients were subjected to ERCP at various periods after cholecystectomy. In this selected patient material there was a 56% incidence of morphological abnormalities in the biliary system, stenosis of the papilla and choledocholithiasis being the most frequent pathological findings. Laboratory examinations proved to be irrelevant with respect to the morphology of the bile ducts. A direct relationship between the clinical symptoms and the surgical procedure was established only in cases presenting with biliary duct stenosis (11% of all cases examined). In the majority of patients the postcholecystectomy complaints were due to incorrect surgical indication or inadequate surgical technique. Postcholecystectomy syndrome can be prevented by more accurate evaluation of the patient prior to and during surgery.

Adult↗

[The pathological endoscopic pancreatogram diagnostic value of radiomorphological changes (author's transl)].

The specificity of abnormal radiomorphological patterns in the endoscopic retrograde pancreatogram (ERCP) has been studied. Out of 3,000 ERCPs 381 contained pathological findings in the pancreatic duct, all of which was subsequently checked by histology. Comparison of the radiomorphologic data and the histologic abnormalities has revealed that ductal abnormalities are not specific to the underlying pancreatic disease. There are, however, changes in the radiomorphologic appearance which, owing to their greater incidence, may be regarded as characteristic to some pathologic process. Solitary stenosis or complete obstruction indicate the presence of tumour, nonsegmental extended dilatation points to papillary stenosis, filling of cavities reveals cysts, while diffuse abnormalities occur most frequently in chronic pancreatitis. Opacification of the bile ducts may yield complementary data, although their specificity is not absolute either. Nonsegmental stenosis of the intrapancreatic bile duct indicate chronic inflammation, while irregular narrowing supports the diagnosis of pancreatic tumours. Arc-shaped dislocation of the bile duct is frequently observed in response to cysts, stenosis confined to the ampullary segment and associated with dilated biliary system are characteristic findings in papillary stenosis. Thus the diagnostic value of the abnormal pancreatogram may be enhanced by simultaneous study of the biliary morphology

Cholangiopancreatography, Endoscopic Retrograde↗

Sulpiride and thyrotrophin releasing hormone loading test in patients with acromegaly.

The effects of sulpiride, a dopamine receptor blocking agent, and of thyrotrophin-releasing hormone (TRH) were studied on prolactin secretion in 17 patients with acromegaly and 25 control subjects. THe basal serum prolactin level was increased in 9 acromegalic patients. After sulpiride loading, maximum changes in prolactin level were significantly smaller in acromegalic patients, irrespective of the basal prolactin concentration. TRH loading resulted in a decrease of prolactin secretion predominantly in the patients with high basal serum hormone levels. A blunted thyrotrophin response to TSH was found only in those acromegalic patients who had concomitant thyroid disease. Higher than normal basal prolactin levels in some of the acromegalic patients and abnormal prolactin responses following sulpiride and TRH loading in most of the patients with acromegaly are attributed to deranged hypothalamo-hypophyseal regulation.

Acromegaly↗

[Endoscopic papillotomy - a new therapeutic approach to gall bladder diseases (author's transl)].

Endoscopic papillotomy (EPT) was performed in 66 patients, 59 of whom had choledocholithiasis and the remaining seven had stenosis of the papilla of Vater. The stones passed spontaneously in 37 patients, but had to be extracted in 10 cases. All seven patients with stenosis showed free bile flow following EPT. Four patients become anicteric although the stones persisted. Four patients had a febrile complication which subsided in response to antibiotic therapy.

Aged↗

[Endoscopic retrograde cholangiopancreatography in the differential diagnosis of chronic pancreatitis and pancreatic cancer (author's transl)].

The endoscopic retrograde cholangiopancreatography (ERCP) findings in 30 patients with chronic pancreatitis and 25 cases of pancreatic cancer are presented in this report. The diagnosis was confirmed in every case by surgery or at autopsy. ERCP was found to be a reliable means of differentiating between pancreatic cancer and chronic pancreatitis in most cases. Multiple lesions are typical of chronic pancreatitis. In solitary lesions a diagnosis can be reached only by consideration of the pancreatographic findings in conjunction with the clinical picture.

Cholangiography↗

[Diagnostic features of the abnormal endoscopic pancreatogram (author's transl)].

Features of 75 abnormal pancreatograms are analysed. Radiomorphology is conferred with surgical or postmortem findings in all cases. None of the anatomical alterations was found to be specific for any given diseases entity, some consistency was verified however. Solitary stenosis suggests cancer. Diffuse alterations point to chronic pancreatitis. Cave filling is a likely sign of cyst or pseudocyst. Since, however, these features are nonspecific, the diagnosis must be based on clinical data as well.

Calculi↗

Diagnostic value of endoscopic retrograde cholangio-pancreatography in biliodigestive anastomoses.

Endoscopic retrograde cholangio-pancreatography performed in patients with bilodigestive anastomosis may furnish not only reliable radiograms revealing abnormal morphology of the two duct system but allows also endoscopic investigation of the stoma, which is often of equal diagnostic value in such patients. The size of the anastomosis is of crucial importance in such complications as cholangitis and secondary bile stone formation. In a significant portion of patients with biliodigestive anastomoses, i.e. in 75% of the present patient material, a morphologic abnormality could be demonstrated offering in many if not most cases the possibility of a surgical correction and eventual cure of the symptoms.

Adult↗