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Biomedical subjects

E Klug

Publications and source records attributed to E Klug.

At least 109 records · Page 6Linked to original sources
PubMed1975

[Systematic approach for investigating basic drugs by paper- and thin-layer chromatography (author's transl)].

The systematic approach described for investigating basic (pharmaceutical) drugs with the aid of paper and thin-layer chromatography relies on the principle that the positions of the spots created by a certain substance on various chromatograms in relation to 5 to 7 test substances and developed together with the sample are indicated by a digit code. With a pre-determined sequence of application of the solvents, code numbers are formed by writing down these digits (supplemented by indices), which are characteristic of the components of the mixture. The code numbers are in all cases clearly distinctive even in the case of a large number of different substances (e.g. 300) if the number of appropriately chosen developing solutions is increased to 6. Evaluation of the code numbers can be carried out with tables or with the aid of punch cards.

Chromatography, Paper↗
PubMed1975

Results of long-term storage of stallion semen frozen by the pellet method.

Stallion semen frozen by the pellet method showed no significant loss of sperm motility and fertility over long periods of storage in liquid nitrogen. Eighteen of thirty mares conceived after insemination with semen recovered in nine ejaculates from seven stallions and stored for 18 months to 7 years.

Animals↗
PubMed1975

Results of insemination of mares with fresh and frozen stallion semen.

Artificial insemination using deep-frozen semen was performed on 116 mares in 1973 using twelve ejaculates from eight stallions of the Hanoverian breed. Despite the fact that the quality of the semen used was poor, the majority of the mares inseminated were subfertile and some mares were inseminated during one oestrus only, 44% nevertheless conceived and gave birth to live foals. Of a small group of ten mares inseminated in the same year with fresh semen, seven conceived.

Animals↗
PubMed1975

Recent observations concerning Klebsiella infections in stallions.

A high incidence of Klebsiella contamination in German 'Warmblut' and Thoroughbred stallions is reported. The organism was recovered from the nostrils, prepuce, pre-ejacultory secretion and, in some cases, on the body surface, in the faeces and on the ground of the covering (mating) yard. Fertility was not affected. However, differences of virulence were observed and Type 5 proved to be the most pathogenic.

Animals↗
PubMed1975

The use of Gn-RH for controlling the oestrous cycle of the mare (preliminary report).

Clinical tests with synthetic gonadotrophin-releasing hormone (Hoechst) were made during the breeding seasons of 1973 and 1974, using 128 mares injected with 1-0 to 4-0 mg of the substance intramuscularly. The mares were placed in one of five groups based on ovarian condition determined by clinical evidence. Some success was obtained in the induction of ovulation in mares with inactive and sub-normally active ovaries and in a small group having cystic ovaries. A large proportion of mares having a mature follicle responded within 48 hr, but others with atretic follicles failed to respond. The usefulness of Gn-RH for this purpose is discussed.

Animals↗