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Biomedical subjects

E Kis

Publications and source records attributed to E Kis.

28 records · Page 2Linked to original sources

Neonatal abdominal cystic masses: spontaneous regression demonstrated with ultrasound.

Abdominal cyst was diagnosed in 14 babies by ultrasound examination (9 multicystic dysplastic kidneys, 4 ovarian cysts, 1 bowel duplication). The cysts were followed in 6 patients by ultrasound and marked reduction of multicystic dysplastic kidneys was observed in 2 patients, and 1 ovarian cyst fully disappeared. Their experience in agreement with the literature data suggest that conservative management with sonographic reevaluation is an acceptable alternative to surgical therapy in uncomplicated cases.

Abdomen↗

[Ultrasonic follow up of spontaneous regression of neonatal abdominal cystic changes].

Abdominal cyst was diagnosed in 14 babies by ultrasound examination (9 multicystic dysplastic kidneys, 4 ovarian cysts, 1 bowel duplication). The cysts were followed up in 6 patients by ultrasound, and marked reduction of multicystic dysplastic kidneys was observed in 2 patients, and 1 ovarian cyst was disappeared. Their experience and a review of the literature suggest that conservative management with sonographic reevaluation is an acceptable alternative to surgical therapy in uncomplicated cases.

Abdomen↗

Bacterial colonization of newborn infants in an intensive care unit.

Bacterial screening of external ear, umbilical and gastric fluid samples from infants at admission to the intensive care unit yielded opportunistic pathogens in 22% and 12% in the years 1980 and 1982, respectively. As a result of improved hygienic measures and more rational use of antibiotics, bacterial colonization of infants staying longer than 3 days decreased from 56% to 19%. Antibiotic treatment is not indicated if opportunistic pathogens except Streptococcus agalactiae (group B), are cultured from infants without clinical symptoms.

Anti-Bacterial Agents↗

[Iron-deficiency and replacement in infancy].

The frequency of iron-deficiency anaemia was investigated in 376 children with the aid of serum ferritin determinations. The children, resident in Budapest or Miskolc were 6 months to 3 years old. Marked iron-deficiency (serum ferritin less than 10 micrograms/l) could be demonstrated in 33.8% of the investigated population. The frequency of iron-deficiency was related to the socio-economic and cultural status of the mother, a factor which is thought to influence the feeding habits. In areas where iron-deficiency is frequently detected regular iron-prophylaxis is recommended.

Anemia, Hypochromic↗

Haloperidol attenuates beta-amyloid-induced calcium imbalance in human fibroblasts.

BACKGROUND: Antipsychotics are widely used in the treatment of behavioral and psychological symptoms of dementia. A low frequency of Alzheimer's disease in patients with schizophrenia is reported, and it has been proposed that antipsychotic medications, such as haloperidol, may be responsible. Disruption of intracellular calcium levels is considered to play a key role in beta-amyloid-induced neurotoxicity in Alzheimer's disease. Haloperidol has also been reported to interact with calcium homeostasis through dopamine-2 and sigma-1 receptors, and other, yet unknown mechanisms. OBJECTIVE: Therefore, we investigated whether differences in the basal intracellular free calcium levels of cultured cutaneous fibroblasts--cells that do not express dopamine-2 and sigma-1 receptors--derived from sporadic Alzheimer patients and from age-matched control individuals after haloperidol treatment might be present. METHODS: Intracellular calcium level was measured in Fura-2AM-loaded human fibroblasts by dual wavelength spectrofluorimetry. RESULTS: Alzheimer cells exhibited significantly lower calcium level as compared to the control cultures. Exposure of fibroblasts to beta-amyloid peptide resulted in increased calcium concentration of the control cells, but not of Alzheimer fibroblasts. Co-incubation of cultures with a therapeutic dose of haloperidol blocked the beta-amyloid-induced elevation of calcium. CONCLUSION: This finding indicates that haloperidol efficiently countervails ionic imbalance and suggests that it may serve as a potential agent in alleviating neurotoxic effects of beta-amyloid peptide.

Aged↗