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Biomedical subjects

E Kinnunen

Publications and source records attributed to E Kinnunen.

61 records · Page 4Linked to original sources
PubMed1983

The epidemiology of multiple sclerosis in Finland: increase of prevalence and stability of foci in high-risk areas.

Reliable data on the epidemiology of multiple sclerosis (MS) in Finland are available from 1964 and 1972. They show that the whole country is a high-risk area of MS with clustering in the western part. A reassessment of the prevalence data was carried out in the southern province of Uusimaa and in the western province of Vaasa, the prevalence day being January 1, 1979. The age-adjusted prevalence was 52.9 per 100,000 in Uusimaa and 92.9 per 100,000 in Vaasa, figures that were three times higher than those recorded for the same areas in 1964. The communities with the highest prevalence rates in the province of Vaasa were the same as those in the survey of 1972; some rates exceeded 200 per 100,000. The increase in the prevalence rates may be due to a better registration of MS cases, but it may also represent a true increase, a possibility that only can be answered by further incidence studies.

Adolescent↗
PubMed1983

The incidence of optic neuritis and its prognosis for multiple sclerosis.

An incidence study of idiopathic optic neuritis (ON) was carried out in 2 geographic areas of Finland for the 9-year period 1970 to 1978. The southern province of Uusimaa composes a medium-risk and the western province of Vaasa a high-risk area for multiple sclerosis (MS). The risk for subsequent MS was determined. A total of 315 attacks on ON were recorded in 296 patients. The mean annual age-adjusted incidence for ON in Uusimaa was 2.2 and in Vaasa 2.5 per 100,000 population. The incidence figures remained unchanged all the time. The mean age at onset was 30 years. 19% of ON patients developed MS during the mean follow-up period of 5.1 years. When the life-table method of analysis was used, the probability of developing MS was 38% in Uusimaa and 24% in Vaasa 9 years after acute optic neuritis. In Uusimaa the risk of women for MS was significantly higher than in men. In 47%, the MS symptoms and signs developed within 1 year and in 90% within 5 years after the initial bout of ON. It is possible that only one part of idiopathic ON cases do have a relationship with MS.

Adolescent↗
PubMed1982

New cases of neurosyphilis in Finland.

A more than tenfold increase in the annual incidence of infectious syphilis occurred in Finland during the 60s. Since then about 4 cases per 100 000 per year have been reported to the Central Medical Board. During the 70s, 39 new cases of neurosyphilis, verified by clinical and serological examinations, were recorded. At least 14 of these patients were primarily infected after 1955. The data suggest that new cases of neurosyphilis may turn up in the near future and indicate that intensified epidemiological control is still needed.

Adult↗
PubMed1981

[Neurosyphilis].

Explore the source record for details and available documents.

Diagnosis, Differential↗
PubMedDate not supplied

Prevalence and prognosis of epilepsy in patients with multiple sclerosis.

An analysis of 599 clinically definite multiple sclerosis (MS) patients including all known cases of the southern province of Finland in January 1, 1979 revealed epileptic seizures in 21 (3.5%) patients. On that date, 12 patients needed treatment (2.0%). The age-adjusted prevalence of active epilepsy was significantly higher than that in the general population. The percentage of partial seizures (67%) was significantly increased in proportion to a series of 100 adult epilepsy patients, with a comparable age distribution. In 10 patients (including three patients with symptomatic epilepsy), the attacks appeared before the MS symptoms. The mean follow-up after the first seizures was 19.3 years. In 10 patients, the seizures disappeared totally during the surveillance until September 1985. Our results show an increased comorbidity between MS and epilepsy. In most cases, however, the prognosis of epilepsy was good and there seemed not to be any clear correlation between the severity of MS and epilepsy.

Adult↗
PubMedDate not supplied

Low-field MRI in the evaluation of rheumatoid cervical spine. Comparison with neurological findings and routine plain radiography.

The usefulness of a low-field magnetic resonance imaging (MRI) instrument in the evaluation of cervical spine abnormalities was studied in 20 patients with rheumatoid arthritis and known anterior atlantoaxial subluxation (AAS) (16 patients) or other cervical spine abnormalities (4 patients). The MRI results were compared with routine plain radiographs and with neurological findings. Three patients had a clinical suspicion of cervical spinal cord compression. This was confirmed by MRI, which additionally detected one more patient with compressive myelopathy. Anterior AAS in MR images was seen in 4 patients, but proper flexion images were not obtained. Atlantoaxial impaction was detected by a recent method of Sakaguchi-Kauppi in 16 patients as compared to 9 patients by the McGregor method and 4 patients by MRI. Most of the clinically important consequences of rheumatoid cervical spine are seen with a low-field MR imager, but detailed bony changes and precise measurements are better evaluated with plain X-rays.

Adult↗