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Biomedical subjects

E Katona

Publications and source records attributed to E Katona.

At least 55 records · Page 3Linked to original sources
PubMed1975

Anesthesia and the golgi apparatus: enzyme activity changes in a golgi-rich fraction of rat liver after a short ether anesthesia.

Activity changes of enzymes in isolated rat liver Golgi preparations at different times (1-48 h) after a short ether anesthesia are reported. Activity of galactosyl-transferase showed a slight gradual increase but thiamine pyrophosphatase decreased sharply, and after 24 h increased to above control level. Arylsulphatase-A remained largely unchanged, and B was significantly decreased. Acid phosphatase activity did remain at the control level, but alkali phosphatase showed a gradual and highly significant increase. Five other enzymes representing probable contaminations from other subcellular organelles, have also been assayed. Correlation is sought between the enzyme activity changes and some other metabolic effects of anesthesia.

Acid Phosphatase↗
PubMed1975

Early effects of aminonucleoside on enzymes in the Golgi apparatus of rat liver.

Rats were injected with a single intravenous dose of aminonucleoside (AMN) and sacrificed 1-48 h later. The activity of several enzymes was assayed in the Golgi apparatus isolated from the liver. Galactosyltransferase activity showed little changes after the AMN, but both acid (EC 3.1.3.2) and alkaline phosphatase (EC 3.1.3.1) activities increased within the first hour and reached control levels only 5-24 h later. Thiamine pyrophosphatase and arylsulfatase A (EC 3.1.6.1) activities also increased and stayed at higher levels for the duration of the experiment. Arylsulfatase B (EC 3.1.6.1) activity decreased shortly after the AMN but later increased to above control levels. These findings support earlier results in which liver ultrastructural and biochemical changes were observed early before renal lesions and proteinuria.

Acid Phosphatase↗
PubMedDate not supplied

Pro- and antioxidant functions of quinones in mammalian cells.

This article is a brief review of current knowledge concerning some basic concepts about the redox and addition chemistry of quinones, followd by a survey of current information regarding the biochemistry of quinones in mammalian cells and their pro- and antioxidant functions. In recent years it has been recognized that ubiquinone (Coenzyme Q), in addition to its involvement as an electron and proton carrier in mitochondrial and bacterial respiration, acts in its reduced form (ubiquinol) as an antioxidant. The antioxidant activity, together with its high degree of hydrophobicity and its widespread occurrence in biological membranes and in low-density lipoprotein, suggest un important role of ubiquinol in cellular defense against oxidative damage. Degenerative diseases and aging may be manifestations of a decreased capacity to maintain adequate ubiquinol levels.

Animals↗
PubMedDate not supplied

Dynamics and compartmentation of water in certain biosystems.

Investigation performed by nuclear magnetic resonance and by deuteration on the dynamics of water molecules in mammalian blood cells and in amphibian oocytes, muscles and nerves allowed to reveal several populations of cell water molecules. Following up relaxation and exchange processes in cell suspensions, packed cell pellets and in isolated tissues, characteristics of water dynamics and compartmentation in various biosystems are compared.

Animals↗