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Biomedical subjects

E Kanazawa

Publications and source records attributed to E Kanazawa.

At least 37 records · Page 2Linked to original sources

Principal component analysis of intercusp distances on the lower first molars of three human populations.

The distances between the five main cusps of lower first molars were measured on moiré photographs of casts obtained from Japanese, Dutch and Australian Aboriginal children. Principal component analysis of the intercusp distances, log transformed and standardized so that average tooth size was held constant, revealed three sources of shape variation in cusp topography. All populations were similar for scores on component 1 which was concerned with variations in the position of the hypoconulid. The Dutch had lowest scores on component 2 indicating small buccolingual distances compared with mesiodistal, whereas the Australian Aboriginals had the lowest mean score on component 3, expressing the distances between metaconid, entoconid and hypoconulid.

Asian People↗

Cusp height relationships between the upper and lower molars in Japanese subjects.

Relationships of cusp height between the upper and lower first molars and between the deciduous second molars in Japanese subjects were analyzed with the aid of moiré contourography. In permanent molars, the height of the hypoconid had a mean value similar to that of the upper trigonal cusps, indicating that upper and lower functional cusps of the same height occlude with each other. In deciduous second molars, however, hypoconid heights were significantly smaller than trigonal cusp heights. Such differences in cusp height between permanent and deciduous dentition may be related to the function and phylogeny of tooth or jaw movements.

Child↗

Study of the cuspal ridges of the upper first molars in a modern Japanese population.

Materials used were dental casts of the upper first molars of modern Japanese subjects, comprising 29 males and 25 females. Their molar occlusal surfaces were photographed by moiré contourography using the standard trigonal plane. The ridges of a cusp, comprising a central ridge and mesial and distal accessory ridges, were identified from the patterns of the moiré fringes. The central ridge was observed in all cusps except for the hypocone in both sexes. Frequencies of the mesial and distal accessory ridges of trigonal cusps were over 90% except for the distal accessory ridge of the metacone, and those of the hypocone were under 25% in both sexes. These values were generally higher in males than in females, especially for the distal accessory ridge of the metacone. The running pattern of the cuspal ridges showed little difference between sexes. The oblique ridge which was higher than the central groove formed a saddle-like structure. This ridge was observed in all materials, but its heights and structural components varied remarkably. In this study, the distal accessory ridge of the metacone was found to be incorporated into the oblique ridge in about 13% of cases. Variability in the running pattern of the ridges within a single cusp was highest in the hypocone and lowest in both the paracone and protocone. The results obtained are considered to represent the stability or reductive tendency of cusps in the upper first molars.

Child↗

Three-dimensional measurement of the occlusal surfaces of lower first molars of Australian aboriginals.

The occlusal surfaces of lower first molars of Australian Aboriginals were measured in three dimensions with the aid of Moiré contourography. Molar cuspal heights in this population were higher than in Japanese (Mongoloid) but lower than in Dutch (Caucasoid) populations. Intercuspal distances were considerably larger than those in the two other populations. Populational differences in occlusal features may influence both craniofacial structures and jaw movements in the three populations. Low correlations between the cuspal heights and the intercuspal distances in the other two populations were also found in this population, indicating that human molar cuspal height is independent of the transverse size of the crown. Mean values for the height of the three principal cusps in lower first molars were less than those in upper ones. However, the height of the hypoconid, which was the highest in the lower molar cusps, showed almost the same mean value as the height of the upper three principal cusps, indicating that the height of the main functional cusp, in both upper and lower first molars, was almost the same.

Asian People↗

Uptake of secondary autoxidation products of linoleic acid by the rat.

Incorporation of secondary autoxidation products (SP) of linoleic acid into the rat body was investigated. Radioactive SP was administered orally to a group of 5 rats, and excretions of radioactive substances in feces, urine and respiration were measured and compared with excretions from rats fed linoleic acid and its hydroperoxides. The SP-fed group excreted 45% and the other groups about 10% of the administered radioactivity through feces. Urinary excretion accounted for 52% of activity ingested in the SP group and less than 30% in the other groups. The 14CO2 produced in each group was about 25% of the ingested activity. Incorporation of the radioactive substances of SP into tissues and organs was measured periodically after administration of a single dose. The radioactive substances accumulated in the liver between 12-24 hr after administration and accounted for 2.6% of the total amount given, the highest level of all tissues and organs. This accumulation led to an elevation of serum transaminase activities, an increase in hepatic lipid peroxide, as determined by thiobarbituric acid test, and a slight hypertrophy of liver (1.5-fold). Therefore, absorbed SP appeared to contribute to the deleterious condition of the liver.

Animals↗