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E Kaldestad

Publications and source records attributed to E Kaldestad.

6 recordsLinked to original sources

[Mental disorders among physicians hospitalized in a psychiatric clinic].

149 physicians were hospitalized in a psychiatric clinic, Modum Bads Nerve Sanatorium, during the period 1958-89. 122 of the physicians were men and 27 were women. The material is selected but is representative of non-psychotic voluntarily hospitalized physicians. More than 1/3 of the physicians had abuse problems, mainly drug abuse. The average age of the physicians was 46, and they had been practising for an average of 17 years at the time of hospitalization. 60% of them worked outside institutions. About 1/3 of them were specialists.

Adult

[Funeral rituals, mourning and mental health].

11 informants who were mourning relatives or friends who had died during the last five years were interviewed by a priest, who asked about their relationship to the deceased, their participation in funeral rituals and their experience of their own mourning process. The respondents endorsed the following scales: SCL-90 Depression subscale, Intrinsic, Extrinsic and Quest Scales, Doctrinal Orthodoxy Scale, Liberal Belief Scale, Moral Conservatism Index and Humanistic Mortality Scale. Each respondent was evaluated hermeneutically in a pastoral-clinical way, and the whole material was treated statistically. The extrinsic person uses his religion to attain comfort, security, and social acceptance, and it is not deeply integrated in his personality. The extrinsic religious orientation correlated positively with a prolonged mourning process and depression. It can be tentatively concluded that extensive participation in funeral rituals seems to prevent a prolonged mourning process and resulting depression.

Adult

Interaction of indomethacin and acetylsalicylic acid as shown by the serum concentrations of indomethacin and salicylate.

A clinical-pharmacological study was performed to determine the effect of acetylsalicylic acid upon the serum concentration of indomethacin. 14 rheumatic patients were given indomethacin orally (25 mg X 4 for 4 days) and concurrently acetylsalicylic acid 3.7 g orally (0.9 g X 3 and 1.0 g X 1 daily), and 21 rheumatic patients were given indomethacin rectally in the morning (100 mg X 1) and concurrently acetylsalicylic acid 3.7 g orally (0.9 g X 3 and 1.0 g X 1 daily). On comparison with treatment with oral or rectal indomethacin alone, it was found that peak serum concentrations of indomethacin were significantly reduced (1% level), the times of the peaks were not shifted, and the areas beneath the serum concentration curves of indomethacin were smaller, but significantly so only if compared with rectal administration. In 12 rheumatic patients given indomethacin by rectum in the evening (100 mg X 1) and concurrently acetylsalicylic acid 3.7 g (0.9 g X 3 and 1.0 g X 1 daily), the serum level of indomethacin on the following morning (after 11 h) did not differ from that found after rectal treatment. A statistically but not biologically significant difference was observed between the mean serum half-lives of indomethacin given orally and rectally. For unknown reasons, concurrent doses of acetylsalicylic acid and indomethacin made the mean serum half-life of indomethacin longer than after its oral administration, but shorter than when the same dose of indomethacin was given rectally. There was no difference between serum levels of salicylate after oral administration of acetylsalicylic acid alone or after a concurrent oral or rectal dose of indomethacin. The results have been related to those reported previously, with respect to the interaction between indomethacin and acetylsalicylic acid, the serum levels of indomethacin after oral and rectal dosing, and the serum half-life of indomethacin based upon a one- or two-compartment model. The clinical relevance of the study is discussed.

Administration, Oral

[Myalgia].

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Analgesics