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Biomedical subjects

E Kékes

Publications and source records attributed to E Kékes.

At least 19 recordsLinked to original sources

[Cardiovascular risk factors in essential hypertension].

Authors analysed the cardiovascular risk factors, their relationship to each other, the rate of multiple appearance in 1476 patients (774 men, 702 women) with essential hypertension. They produced a special questionnaire and risk factor analysing program for performing static and dynamic investigations on the base of international and domestic experiences. The data of their investigations verified, that the occurrence of obesity is very frequent and is associated with abnormal cholesterol and triglyceride values. The appearance of glucose metabolism disorder was in 44% of patients. The rate of metabolic syndrome can be estimated on 25-30% in the hypertensive population.

Adult↗

[Current status and possibilities of distant education in medicine].

Author analyses the concept and methods of distance education. The definition of distance education consist of geographic separation of the learner and the teacher, the high level of educational organisation, the use of modern technology for communication with interactivity. Before the widespread use of electronic communications for teaching and learning, the conventional method for distance education was the books and postal service. Since the mid 1980's the attention shifted to the computer technology and computer networks the internet is radically different with previous electronic media. Pfaffenberger estimated in 1994, that by 1998 about 100 million people would have access to the Internet. The web servers gives a multimedia environment, which potencially can provide a truely integrated teaching and learning system to educators worldwide.

Communication↗

[Captopril in the treatment of heart failure].

The author takes the characteristic hemodynamic features and neurohumoral factors associated with heart failure as the starting point for the discussion. He specifies fundamentals of the current strategies and goals of the management of heart failure. Treatment with vasodilatator and ACE inhibitors has paved novel way for treatment of heart failure, because it is not only able to alleviate the symptoms, but also to improve hemodynamic parameters and increase survival. Initiation of treatment at early stage (silent ventricular dysfunction) is able to prevent the development of manifest signs of heart failure. Captopril, a classical ACE inhibitor, is suitable for modern treatment of heart failure, as well for prevention of myocardial remodelling following acute myocardial infarction.

Angiotensin-Converting Enzyme Inhibitors↗

Third generation electronic medical record knowledge based perspectives.

There is a need to develop better electronic medical records. One possible solution is to put more and more 'routine' medical knowledge into systems handling medical records. In this paper, we analyze the current state-of-the-art of knowledge-based medical record handling; we mainly consider the work of Rector et al. [1]. We offer a more detailed 'four level' knowledge level model compared to the 'two level' model of Rector. The EMR of the future might be approached with a top-down method, using the above mentioned 'four level' model.

Artificial Intelligence↗

[Antianginal effect of transdermal isosorbide dinitrate (multicenter study)].

Efficacy of transdermal isosorbid-dinitrate spray was investigated in 167 of 254 patients with stable angina pectoris. The transdermal application of isosorbid-dinitrate decreased successfully the number of anginal attacks and the sublingual nitroglycerin or isosorbid-dinitrate consumption. Very few side effects were observed and the patients well-being was good during treatment.

Administration, Cutaneous↗

[Dual-chamber rate responsive cardiac pacing].

The authors describe in this report their first experience with the implantation of a rate responsive, dual chamber pacemaker. They emphasize the advantages of this type of pacemakers: the maintenance of AV-synchrony and the rate increase in response to exercise. Meanwhile they call attention on the complexity of the ECG interpretation.

Adult↗

Anti-anginal effect of Tenormin (atenolol).

The anti-anginal effect of Tenormin (atenolol) has been examined besides placebo control by single blind method in 20 patients with ischaemic heart disease, suffering from stable effort angina proved by coronarography. It has been observed that atenolol significantly decreases the weekly number of anginal attacks, and the amount of sublingual nitroglycerin consumption. It has been proved that atenolol successfully prevents the exercise-induced elevation of blood pressure and heart rate, increases exercise tolerance, decreases myocardial O2 consumption. The place among beta-blockers of the cardioselective, low lipophilic atenolol, which lacks membrane stabilizing and partial agonist activity, has been discussed. The administration of a single daily dose (one 100-mg tablet), selective cardiac effect, lack of unwanted side-effects (cold extremity, nightmare, insomnia, etc.) are the advantages of the drug.

Adult↗

Comparative evaluation of the effect of balloon dilatation by exercise precordial mapping and exercise 201-thallium scintigraphy.

Precordial exercise electrocardiographic mapping and exercise 201-thallium scintigraphy were simultaneously used on sixteen patients before, shortly after and three months after percutaneous transluminal coronary angioplasty (PTCA) to evaluate the immediate and late results of the intervention. In spite of the limited number of observations, positive exercise precordial mapping and or a reversible 201-thallium perfusion defect after PTCA seem to be indicative of failure of balloon dilatation or of development of restenosis in a given coronary artery. "Reverse minimum", that is the minimum in the resting precordial map which disappears on exercise, may be a sign of segmental coronary artery occlusion and well functioning collateral supply.

Adult↗

Captopril in heart failure.

The renin production, angiotensin II and aldosterone plasma levels have been proved to occur in heart failure. This pathological abnormalities can be stopped by the inhibition of ACE. This action of captopril is accompanied by a favourable clinical effects, the improvement of the symptoms of heart failure and the increase of sodium and water excretion and the increase of serum potassium level.

Biomechanical Phenomena↗

Non-invasive assessment of elevated ventricular diastolic pressures in patients with ischaemic heart disease.

For non-invasive assessment of the diastolic pressures of both ventricles, 50 patients with ischaemic heart disease were studied by combined mechano- and echocardiography. Twenty one patients had pulmonary congestion, eleven had acute mitral regurgitation and 18 had signs of left and right heart failure. All patients had undergone cardiac catheterization. The diastolic parts of apexcardiograms (left and right ACG) and the morphological alterations of mitral and tricuspid valve echograms were analysed. Using the invasive and non-invasive data of three groups a non-invasive diastolic pressure scale for both ventricles could be construed.

Adult↗