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Biomedical subjects

E K Fishman

Publications and source records attributed to E K Fishman.

At least 325 records · Page 18Linked to original sources

Biliary cystadenoma and cystadenocarcinoma: CT and sonographic findings.

Biliary cystadenomas and cystadenocarcinomas are rare cystic neoplasms, usually intrahepatic in location, that are characterized pathologically by a multilocular appearance. We report the CT and sonographic findings in eight cases of biliary cystadenoma and three cases of biliary cystadenocarcinoma and correlate them with the surgical and pathologic findings. CT showed internal septa in eight of the 10 multiloculated lesions, whereas sonography showed septa in all five cases in which it was used. CT in two of the three cystadenocarcinomas showed thick and coarse mural and septal calcifications as well as large solid soft-tissue masses in one. CT showed mural soft-tissue nodules in the single case of a unilocular cystadenocarcinoma. Sonography and CT usually show the multilocular nature of biliary cystadenomas and cystadenocarcinomas. The presence of mural or septal nodules, discrete soft-tissue masses, and possibly thick and coarse calcifications increase the likelihood of a cystadenocarcinoma.

Adult↗

Computed tomographic features of renal osteodystrophy.

The spectrum of musculoskeletal abnormalities seen on routine computed tomographic (CT) examinations of five patients with renal osteodystrophy are described. CT findings included multiple brown tumors, osteitis fibrosa cystica, abnormal sacroiliac joints, periarticular tumoral calcifications, prominent Schmorl's nodes, and slipped capital femoral epiphyses. In this small group of patients, the musculoskeletal abnormalities ranged from the subtle to the dramatic. Although CT examination is rarely used as a screening test for renal osteodystrophy, it is important to be familiar with its many appearances on CT, in order not to confuse the CT changes of renal osteodystrophy with metastatic disease, osteomyelitis, or inflammatory arthritis.

Adolescent↗

Krukenberg tumors: CT features and growth characteristics.

We reviewed the computerized tomographic features of pathologically proven metastases to the ovary in 12 patients. Serial CT scans were available in nine of the 12 patients--before removal of the ovaries in five cases (showing typical growth characteristics of these metastases) and afterward in six (showing common patterns of tumor progression). Primary neoplasms metastasizing to the ovary included adenocarcinoma of the colon (seven), stomach (two), appendix (one), and endometrium (one), and carcinoid tumor (one). On CT, metastases to the ovary were large lobulated or oval masses with cystic and solid components. Nine were bilateral and three were unilateral. Three patterns of ovarian enlargement were seen: macrocystic (six), microcystic (three), and predominantly solid enlargement with necrosis (three). Other associated CT findings included carcinomatosis, hydronephrosis, ascites, liver metastases, and lymphadenopathy. The primary tumor in patients without a prior history of malignancy was identifiable retrospectively on CT in four of the five cases.

Adult↗

CT of the small bowel and mesentery.

The detection and definition of small bowel pathology is a frequent clinical and radiologic problem. Although contrast radiography and enteroclysis are the primary means of evaluating the small bowel, computed tomography (CT) has become increasingly important as a complementary examination. Initial diagnoses proffered by barium studies may be further characterized by CT and this additional information may have significant impact on patient management.

Humans↗

CT of the gut in the immunocompromised host.

The spread of the acquired immunodeficiency syndrome, the increasing popularity of bone marrow, renal, and other organ transplants, and the development of potent immunosuppressive drugs have produced a large population of immunocompromised hosts. These patients are at great risk for developing both opportunistic infections and neoplasms such as Kaposi's sarcoma and lymphoma. The gastrointestinal complications and computed tomographic manifestations of these previously rare disorders are discussed.

Acquired Immunodeficiency Syndrome↗

Clinical applications of volumetric three-dimensional imaging. A report of three cases.

Three-dimensional imaging has evolved rapidly. We believe that volumetric image processing (VIP) represents a major advance within this modality. VIP preserves the fidelity of the original computed tomography (CT) data and allows the viewer to interact with the images in real time. This complements and integrates the information acquired on two-dimensional CT studies, as illustrated in three representative cases.

Adult↗

Two-and three-dimensional imaging of the painful shoulder.

Fifty-six patients with musculoskeletal disorders involving the shoulder were examined using two-dimensional computed tomography multiplanar reconstruction and volumetric three-dimensional (3D) image processing. Two- and three-dimensional imaging of the shoulder demonstrated advantages over conventional radiography in clarifying areas of complex anatomy. The techniques were found most beneficial for (1) delineating complex fractures; (2) evaluating joint instability; (3) localizing foreign bodies; (4) detecting lytic lesions; (5) assessing soft tissue pathology; and (6) identifying causes for decreased range of motion. Two-dimensional multiplanar reconstruction provided superior views of the scapula and permitted a better understanding of the orientation of the glenoid. Multiplanar reconstruction displayed deep soft tissue anatomy more clearly, including the course of important neurovascular structures. Volumetric 3D imaging added several unique perspectives, providing a more comprehensive representation of the shoulder and its articulating surfaces. The ability to rotate the shoulder about he vertical and horizontal axes in an animated video loop and to edit away confusing, overlying structures provided a "real-time" 3D model of the shoulder for planning treatment.

Humans↗

Mediastinal adenopathy and endobronchial involvement in metastatic renal cell carcinoma.

Mediastinal adenopathy and endobronchial metastases are sometimes the only radiological manifestation of metastatic disease from extrathoracic neoplasms. We report on four patients in whom hilar and paratracheal adenopathy (n = 3) and endobrochial involvement (n = 1) were the only intrathoracic manifestations of metastatic renal cell carcinoma. Three of the patients had nephrectomies 9 months to 4 years before the appearance of intrathoracic disease; another patient presented with medastinal disease as the initial manifestation of renal cell carcinoma. If a patient with a history of renal cell carcinoma develops pulmonary hilar adenopathy, metastatic disease should be suspected and appropriate diagnostic measures should be taken.

Bronchial Neoplasms↗

Computed tomography and magnetic resonance imaging diagnosis of thymic cyst.

A case of mediastinal thymic cyst evaluated by computed tomography and magnetic resonance imaging is presented. The anterior mediastinal mass was well-demarcated and measured 10 Hounsfield units on the computed tomographic scan. The lesion showed intermediate signal intensity on T1-weighting and became hyperintense on T2-weighted images. These computed tomography and magnetic resonance imaging features suggested a cystic structure, which proved to be a benign thymic cyst on pathologic examination.

Child↗

Complications of acute diverticulitis of the colon: improved early diagnosis with computerized tomography.

We have evaluated the diagnostic role of computerized tomography in 42 patients suspected clinically of having a complication of acute diverticulitis (abscess, colovesical fistula, or both). Diverticular abscesses were confirmed at operation in 10 patients. All 10 patients were diagnosed preoperatively on computerized tomography by the triad of diverticula, a segmentally thickened colon, and extravisceral fluid collection with (6 patients) or without (4 patients) associated gas. Contrast enema study suggested the presence of a diverticular abscess in only two of eight patients studied. Colovesical fistulas were confirmed in 12 patients. Eleven of 12 were diagnosed preoperatively on computerized tomography by the triad of air in the bladder, thickened colon adjacent to an area of thickened bladder, and the presence of colonic diverticula. Contrast enema examinations demonstrated the fistula in only three of eight patients studied. The remaining 20 patients proved to have uncomplicated acute diverticulitis. Findings on computerized tomography included the presence of a segmentally thickened colon with diverticula but without the findings of an abscess or a colovesical fistula. Computerized tomography correctly visualized acute diverticular complications in 21 of 22 patients and it excluded an abscess or fistula in all 20 patients with uncomplicated acute diverticulitis who were suspected of having a diverticular complication. Computerized tomography is the most sensitive and specific test for diagnosing complications of acute diverticulitis. It should be an early consideration in patients with suspected diverticular abscesses or fistulas so that appropriate therapy is not delayed.

Abscess↗

Fractures of the sacrum and sacroiliac joint: evaluation by computerized tomography with multiplanar reconstruction.

Conventional roentgenographic views of the pelvis provide inadequate assessment of complex bony trauma. Computerized tomography (CT) allows simpler patient positioning, more reliable detection of subtle fractures, better characterization of complex fractures, and detection of associated soft tissue and joint space abnormalities. The addition of multiplanar reconstructions (MPR) provides a better understanding of the pathoanatomy. The sacrum and the sacroiliac joint, traditionally problematic to image, are particularly well defined by CT/MPR. Subtle diastasis and intra-articular fragments are more reliably detected when the transaxial image is supplemented by coronal reconstructions. The degree of comminution and direction of fragment displacement are also best defined by coronal and sagittal formatting. Surgeons often find this protocol useful in preoperative assessment of extent and stability of fractures, and in planning conservative or surgical management.

Adult↗