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Biomedical subjects

E Johnson

Publications and source records attributed to E Johnson.

At least 379 records · Page 21Linked to original sources

A circumferentially-sensitive miniature pressure sensor for study of human esophageal motility.

Manometric systems in current use for study of human esophageal motility consist of sensors with a restricted radial disposition. Since both upper and lower esophageal sphincters are asymmetrical structures, such sensors are not ideal for sphincteric pressure measurements. In this report, we describe a circumferentially sensitive sensor (MT) which consists essentially of a miniature transducer mounted within a sealed fluid-filled chamber, surrounded by a pressure-sensitive silastic diaphragm. This device is accurate and sensitive. It was compared in 10 young healthy men with a standard perfused catheter system (PC) composed of three catheters, whose side openings were at the same axial level, connected to external transducers. Pressures recorded from the lower esophageal sphincter were significantly higher with the MT than with the PC; and in the upper esophageal sphincter, the rapid pressure changes associated with deglutition were far more faithfully reproduced with the MT. Contractile pressures recorded after swallowing from the body of the esophagus were similar with the two systems, provided that catheters were perfused at a rapid rate (approximately 8 ml/min for each catheter). This preliminary evaluation indicates that this MT has significant advantages as compared with currently available systems.

Adult↗

Unreliability of direct antibiotic susceptibility testing on wound exudates.

Direct susceptibility testing was performed on 110 specimens of wound exudates. Growth was inadequate in 76 of these specimens. Of the remaining 34 specimens, only 5 produced results corresponding to those obtained by testing individual bacterial isolates by the Kirby-Bauer technique. This study confirms that direct susceptibility testing of wound exudates may provide misleading and clinically unreliable information on more than 95% of specimens.

Exudates and Transudates↗

Epilation of growing hair follicles.

Epilated growing follicles continue to grow. They produce a length of hair which is shorter than that produced by intact follicles over the same period of time, because they grow for a shorter time and at a lower rate.

Animals↗

Formation of temporary flagellar structures during insect organogenesis.

Cilia and flagella are rare in nongerminal tissues of anthropods, and are generally thought to be restricted to sperm and sensory cells in insects (2). Whitten (5) has reported the presence of kinetosomes at the base of mitotrichia in the dipteran fly Sarcophaga bullata, but reports no evidence of the organization of fibrous elements characteristic of cilia and or flagella. During an ultrastructural analysis of morphogenesis of the colleterial gland of the silk moth Hyalophora cecropia, we found the first example of paired flagella associated with an insect secretory cell. These structures are also unusual in that they serve a temporary role in morphogenesis and subsequently disappear at the terminal stages of differentiation.

Animals↗

A goal list and a treatment methods index in an automated record system.

In conjunction with the development of a computerized goal-oriented record system at Forest Hospital Des Plaines, Illinois, research staff developed a psychiatric goal list from goal statements most frequently used at the hospital. Treatment methods written by hospital staff were also reviewed and classified under the goal statement for which they were most frequently written. The result is the Treatment Methods Index, which currently contains more than 500 goal statements and 1500 treatment method statements, and also lists all drugs and activity therapies used in the hospital. The index is stored in a computer, and a comprehensive treatment plan can be generated by entering the numbers of selected goals and treatment methods. The authors emphasize the advantages of the system in writing and updating treatment plans and its importance in peer review and other medical-care evaluations.

Automation↗

Adopting new models for continuity of care: the ward as mini-mental-health-center.

Several years ago the staff of a traditional psychiatric ward in a Veterans Administration hospital began trying to provide continual care for their former inpatients after they left the hospital. Nursing assistants conducted basic-skills groups and other groups in board-and-care homes; staff members made themselves available to former inpatients and theri families, roommates, or board-and-care sponsors through a 24-hour telephone service and home visits; and a day-care program and follow-up groups for the ward's outpatients were set up. Later the staff establiched additional day-care and follow-up programs in a downtown satellite unit. In a recent three month period, patients made a total of 4488 visits to the satellite and hospital programs. The preceding paper discusses some of the theoretical considerations on which this program and other alternatives to traditional care are based.

Aftercare↗

Distribution of Serratia species in clinical specimens.

Eighty-five strains of Serratia were speciated. The majority were Serratia marcescens and were recovered from a variety of clinical specimens. S. liquefaciens and S. rubidaea were recovered only from sputum.

Anti-Bacterial Agents↗