Biomedical subjects
E John
Publications and source records attributed to E John.
Respiratory support in hyaline membrane disease impact on mortality in babies over 1000 grams.
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[Anthropometric studies in healthy children of a large town. I. Methods].
Based on the development of systematic investigations into child growth in the GDR, the importance of normal values of exact anthropometric parameters, which have to be checked every 10 years, is to be emphasized. For this reason, 1500 patients of the Pediatric Clinic of the Erfurt Medical School in the age between 1 and 3,5 years, were anthropometrically measured applying the slightly modified definitions by Martin-Saller 1959. Body length, trunk length, width of shoulders and pelvis as well as 10 limb measures and 7 skull measures were taken.
[Anthropometric studies in healthy children of a large town. 2. Results and normal values].
Mean values and standard deviations found in a population of 1500 children in the age between 1 and 3,5 years of 21 anthropometric parameters are given. They are statistically different and can be used as normal values. The growth of boys and girls is shown to be steady with age, in particular, as for as length and width measures are concerned. There are some significant sex differences. The practical use of the results is tested at present.
Influence of early introduction of continuous positive pressure breathing on the course of hyaline membrane disease.
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Promazine and neonatal hyperbilirubinaemia.
An increased incidence of jaundice in mature, healthy newborn babies was noticed in 1970-1971. This coincided with the increased used of the drug promazine. A decrease in the incidence of jaundice was noted three months after total withdrawal of this drug from the hospital.
Phototherapy in neonatal hyperbilirubinaemia.
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Complications of phototherapy in neonatal hyperbilirubinaemia.
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Pleural effusion in the newborn.
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Echo-virus encephalitis in Pondicherry.
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Phenylketonuria--the first case from the Andhra Pradesh, South India.
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A comparative study of the tubal ring applied via minilaparotomy and laparoscopy in postabortion cases.
Sterilization with tubal rings applied via minilaparotomy or laparoscopy was performed on 300 randomly selected postabortion subjects to evaluate the safety and effectiveness of the two surgical methods. One hundred and forty-nine procedures were performed by minilaparotomy and 151 by laparoscopy. Gas leakage due to equipment problems was the most common technical difficulty during laparoscopy, and difficulty in exteriorizing the tubes was the most common surgical difficulty. Women undergoing laparoscopy experienced significantly less pain during surgery and had significantly lower rates of immediate and early postoperative complications than those women undergoing minilaparotomy. The rates of gynecologic abnormalities at six and 12 months were similar for both procedures. At this writing, no pregnancies have been reported among the study subjects. The results of our study indicate that laparoscopy is superior to minilaparotomy when it is performed in a controlled hospital situation.
Body electrolytes in bronchopulmonary dysplasia and the effects of diuretic therapy.
Body electrolytes and their regulatory hormones were studied in preterm infants who suffered from bronchopulmonary dysplasia under two groups: those who were not treated with diuretics (Group II), and those who were treated with diuretics (Group III). The values were compared with a group of matched healthy controls (Group I). Lower serum Na levels, a need of higher Na intake, and higher urinary Na concentrations and urinary specific gravity were found in Group II infants. FeNa was normal and the urinary flow rate was lower than the controls. These data suggest an inability of these infants to dilute urine. Group III infants who were treated with diuretics showed higher serum Na levels and lower urinary specific gravity than Group II infants. These values, as well as water and Na intake/output ratios, were all similar to the control values. Serum aldosterone level was highest in Group II but did not reach significance. Intracellular K concentration was not different between the groups indicating an optimum total body K balance. A significant negative correlation between serum Na and aldosterone levels was found in Group II infants, which was not noted in the controls. Significant correlations were also found between FeNa and plasma aldosterone level in the BPD groups, unlike the controls. The control group of infants showed significant positive correlation between Na balance and serum Na levels. Our results suggest that inability to dilute urine appropriately might be the reason for the BPD patients to retain body water. Water restriction and diuretic therapy therefore are reasonable therapeutic approaches in such cases.
Renal disorders and diseases of the newborn.
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Unusual manifestations of Henoch-Schonlein purpura.
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Radiological criteria for the diagnosis of pulmonary forms of tuberculous infection.
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Fecal sodium and potassium losses in low birth weight infants.
We measured 24-hour fecal losses of sodium (Na) and potassium (K) in immediate post natal period of preterm neonates to determine the role of this route in the electrolyte imbalances seen in such infants. The values from preterm infants were compared to a group of age matched term infants. Eleven studies were done on unfed extremely low birth weight infants (group I, birth weight < 1200 gms), seven on fed preterm infants (group II, birth weight 1201-2500 gms) and nine on fed term infants (group III, birth weight 2501-4000 gms). Measured and derived variables compared between the groups were 24 hour fecal volume, total fecal electrolyte contents, Na or K lost per kg of body weight and per gm. of stool and Na or K losses as percent of intake. Although 24 hour fecal volume was lowest in group I, none of the variables related to Na differed between groups I and II whereas all of them were significantly lower in group I when compared with group III. Groups II and III differed only in terms of Na loss/gm stool which was lower in the previous group. Conversely K loss/gm of stool was significantly higher in group I when compared with both groups II and III and the only variable that differed between groups II and III was a higher fecal K content as fraction of intake. Fecal K/Na ratio was highest in group I, and decreased progressively with advancing gestational age, whereas creatinine clearance was lowest in group I and increased along with gestational age.(ABSTRACT TRUNCATED AT 250 WORDS)
Renal physiology and acute renal failure.
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