Synthesis of 2,6,10,14-tetramethylpentadecanoic acid (pristanic acid).
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Biomedical subjects
Publications and source records attributed to E Jellum.
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Measurement of glutathione (GSH) in consecutive blood samples from patients with rheumatoid arthritis (RA) revealed, in good responders to D-penicillamine, a 20% to 35% increase in erythrocyte-GSH (E-GSH) levels after 2 to 8 wk of treatment. Usually this rise predicted a clinical response some wk later. Nonresponders to D-penicillamine who did not show an increase in E-GSH could be converted to responders by receiving L-cysteine. E-GSH rose--prior to the clinical response--by up to 50% of pretreatment values. In RA patients with spontaneous changes in disease activity, E-GSH tended to decrease during relapses and increase before remissions.