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Biomedical subjects

E J Stay

Publications and source records attributed to E J Stay.

8 recordsLinked to original sources

Pleomorphic rhabdomyosarcoma arising in association with the right pulmonary artery.

Pulmonary artery rhabdomyosarcomas are rare lesions, with a small number of cases reported in the literature. We report a case of pulmonary artery rhabdomyosarcoma that arose in the right pulmonary artery. The patient presented with cough, chest pain, and hemoptysis and was found to have a sarcoma arising in the right pulmonary artery and extending distally within the pulmonary vasculature into the right lung. The gross pathologic features, microscopic appearance, immunohistochemical profile, and computed tomographic and electron microscopic findings are presented. The site of origin and differential diagnosis of these lesions are discussed.

Adult

Gravidic macromastia: case report.

Gravidic macromastia is a rare condition. Breast enlargement in pregnancy is influenced by several hormones, including ovarian steroids and somatotropic or lactogenic polypeptide hormone. Evaluation showed minimal reactive stromal and periductal fibrosis. The treatment is surgical.

Adult

Tuberculosis and adenocarcinoma of prostate gland.

The coexistence of tuberculosis and various malignancies is common. Although adenocarcinoma of the prostate and genitourinary tuberculosis are seen frequently, their concomitance is extremely rare. The clinical and pathologic features in a seventy-seven-year-old man with these coincident lesions are discussed. The rarity of this concurrence is analyzed, and the factors and theories explaining its dissociation are postulated.

Adenocarcinoma

The relationship between nephroblastoma and neurofibromatosis (Von Recklinghausen's disease).

Three cases with co-existent Wilm's tumor and Von Recklinghausen's Disease from a series of 342 nephroblastomas are discussed as to the significance of this association. Biological arguments favor a positive link because of the multiplicity of associative lesions which parallel each other, the co-existence of which suggests a common genetic bond. An embryologic association is described whereby early mutational events, i.e. neural induction of nephrogenesis, may link these two entities in utero. Further interconnection is stated statistically, in that nephroblastoma patients in this series had a 29 fold higher incidence of multiple neurofibromatosis than predicted for in the general population. The co-existent diseases in the three cases observed are approximately 33-50% more than can be accounted for by chance in the United States population. Malignant transformation in neurofibromatosis is discussed because of the therapeutic implications presented by two of the three Wilms' tumor patients studied.

Child, Preschool

Ovarian tumors in pregnancy. A community hospital's five year experience.

Ovarian tumor in pregnancy is a distressing problem for the obstetrician. A physician must differentiate between a manifestation of a normal physiological condition and a serious pathological condition. Fortunately an ovarian tumor in pregnancy is rare. Once the condition is suspected, a physician should use all available tools to confirm the diagnosis. A patient should be treated accordingly, keeping in mind the age of the patient, the gestational age, and the biology of different types of the tumor.

Adult