Biomedical subjects
E J Smit
Publications and source records attributed to E J Smit.
Frequent detection of high viraemia in HBeAg-negative South African carriers.
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Hepatitis D virus--how prevalent?
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Intramedullary femoral osteosynthesis: an additional cause of ARDS in multiply injured patients?
This study analysed the effects of reaming and intramedullary nailing and thoracic injury related to development of ARDS and multi-organ failure in multiply injured patients. Sixty patients were entered into a retrospective follow-up study. Twenty-one patients with thoracic injury and femoral shaft fracture, treated by intramedullary nailing, were compared with 17 patients with a femoral shaft fracture without thoracic injury, and with 22 patients without femoral shaft fracture but with major thoracic injury. The incidence of ARDS, multiple organ failure (MOF) and the mortality rate in the groups was analysed, using chi 2 and Fisher exact tests. No significant differences in age, sex and ISS existed between the groups. There were no statistically significant differences with regard to the incidence of developing ARDS (P > 0.5), MOF (P > 0.5) and mortality rate (P > 0.2) after injury. The results of this study suggest that reaming of the femoral shaft as part of an intramedullary nailing procedure is not a major cause in developing ARDS and MOF in patients with femoral shaft fractures and thoracic injury. Conventional intramedullary nailing can be considered as a safe procedure in femoral shaft fractures in multiply injured patients, as well as in the presence of major thoracic injury.
An extended QBASIC program for the normalization and computation of whole-cell protein profiles and the application to clinically important Candida species.
The computer program described enables a rapid calculation of relative molecular masses of proteins from different yeasts and microbial pathogens, by interpolation from a molecular weight calibration curve that comprises stepwise linear regression between the protein bands produced by the internal standards. A similarity matrix can then be produced, taking into account variations between calculated molecular masses caused by small differences in bandwidths and/or positions of specific protein bands. This program has been applied to different Candida species and the similarity data obtained further analysed numerically utilizing CLUSTAN II on a SPERRY 1100 multi-processor.
Taxonomic relationships of Cryptococcus and Tremella based on fatty acid composition and other phenotypic characters.
The cellular long-chain fatty acids present in 33 strains, representing 15 species of Cryptococcus, and 4 species of Tremella, were determined by gas chromatography. According to the relative amounts of fatty acid methyl esters, the Cryptococcus species studied were divided into four main groups. Possible relationships between species representing the two genera are presented in a new model, where cellular long-chain fatty acid compositions and other phenotypic characteristics are included.