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Biomedical subjects

E J Schulz

Publications and source records attributed to E J Schulz.

At least 37 records · Page 2Linked to original sources
PubMed1983

Lichen planus dermopathy: demonstration of a lichen planus specific epidermal antigen in affected patients.

Lichen planus is a common papulosquamous disorder of skin and mucous membranes of unknown etiology. Studies reported here demonstrate a lichen planus specific antigen (LPSA) in granular and deep prickle epithelial cells from the lichen planus lesion. Sera from seven out of eight lichen planus patients tested contained an antibody to LPSA. The LPSA was not detected in normal skin tissues from lichen planus patients, or in skin from normal donors and skin from patients with skin disorders other than lichen planus. A serologic survey of serum from people with no clinical history of lichen planus revealed approximately a 7% incidence of antibody to LPSA. These studies suggest that LPSA may be of exogenous origin.

Adolescent↗
PubMed1982

Skin disorders in Black South Africans: a survey of 5000 patients seen at Ga-Rankuwa Hospital, Pretoria.

The skin disorders of 5000 Black patients are surveyed. Th eczemas were by far the commonest group of disorders seen in this series (29%), as they are in Whites, Coloureds and Indians. Acne was second commonest (11%), with a frequency similar to that found in other races. Skin damage resulting from the use of bleaching creams was responsible for 6% of all skin disorders. There was a decrease in coccal infections, syphilis and pellagra compared with previous surveys.

Adult↗
PubMed1978

Treatment of eczema with cyclophosphamide and azathioprine.

Nine patients with eczema were treated with the immunosuppressive drugs cyclophosphamide and azathioprine. In all patients the eczema was severe and incapacitating and had not responded satisfactorily to systemic and topical corticosteroid therapy. The eczema improved in all patients and systemic corticosteroids, which had resulted in undesirable side-effects, could be decreased or stopped. Leukopenia was not necessary for achieving clinical improvement. Several months of treatment were needed to obtain significant improvement in the eczema and long term remissions followed cessation of therapy.

Adrenal Cortex Hormones↗
PubMed1977

Keratolytic winter erythema or 'oudtshoorn skin': a newly recognized inherited dermatosis prevalent in South Africa.

A hitherto undescribed inherited dermatosis, traceable to certain 19th-century inhabitants of Oudtshoorn, CP, has been transmitted as an autosomal dominant to a large number of their present-day descendants. The disease consists of intermittent and recurrent centrifugal peeling, with redness, of the palms and soles in particular. In more severe cases similar patches are found extending up the limbs to the buttocks and the trunk generally. The inconvenience is usually moderate, but it may be incapacitating. Some temporary relief, but so far nothing permanent, can be offered through treatment.

Adolescent↗
PubMed1976

Treatment of erythema nodosum and nodular vasculitis with potassium iodide.

Twenty-four of twenty-eight patients with erythema nodosum and sixteen of seventeen patients with nodular vasculitis responded to treatment with potassium iodide. Relief of symptoms occurred within 2 days. The average duration of treatment was 3 weeks and the lesions took an average of 2 weeks to resolve. The possible mode of action of potassium iodide is discussed and an immunosuppressive effect mediated by heparin is suggested.

Adolescent↗