Search PubMed⌕ Search

Biomedical subjects

E J Porter

Publications and source records attributed to E J Porter.

27 records · Page 2Linked to original sources

The qualitative-quantitative dualism.

Similarities and differences between qualitative and quantitative research methods are presented; various bases for the choice of a methodology are addressed. Practical solutions to the quandaries posed by the qualitative-quantitative dichotomy are explicated, with supporting methodological examples for nursing research studies. Finally, an ontological-epistemological foundation for a human science approach to nursing research is proposed as a means of obviating the qualitative-quantitative dichotomy.

Analysis of Variance↗

Hyperthyroidism and acute bronchial asthma.

Asthma may be very mild, at times hard to diagnose; beta blockade should be used only with great caution. An asthmatic who becomes thyrotoxic should be closely monitored for deterioration of the asthma.

Adult↗

Comparison of effects of intraoperative and postoperative methadone: acute tolerance to the postoperative dose?

The effects of methadone 10 mg administered in two different clinical contexts, at induction of anaesthesia and following operation, were studied in two groups of patients undergoing elective total hip replacement. The intraoperative group received methadone 10 mg i.v. at induction of anaesthesia as part of a balanced anaesthetic technique. The postoperative group received methadone 10 mg i.v. following operation, extradural bupivacaine being used for the operative period. A demand analgesia system delivering methadone i.v. was used after operation in both groups. Arterial blood-gas tensions, cortisol and glucose concentrations, analgesic effects and plasma methadone concentrations were compared in the two groups. The only major difference between the two groups was in analgesic requirement. At the time of connection to the demand system the two groups had the same plasma methadone concentrations. Subsequently, the postoperative group had a significantly greater analgesic requirement which resulted in significantly greater plasma methadone concentrations the following morning. Thus, the administration of methadone following operation appeared to exert less analgesic effect than the same dose given during operation. The reasons for this are discussed.

Adult↗

Sublingual buprenorphine used postoperatively: ten hour plasma drug concentration analysis.

1 A 10 h study of plasma drug concentrations of the opiate buprenorphine after use was designed because a previous 3 h study had shown that peak plasma drug concentrations in some patients had not occurred by 3 h after the sublingual dose. 2 Fifteen postoperative patients were studied: at 3 h after a 0.3 mg intravenous dose five patients received a sublingual preparation of 0.4 mg of buprenorphine, five 0.8 mg of buprenorphine and five placebo. Plasma drug concentrations of buprenorphine were measured by specific radioimmuno-assay. 3 Plasma drug concentrations after sublingual buprenorphine were significantly higher than those in the placebo group by 1 h. They remained significantly higher over the succeeding nine hours. The mean time to peak plasma drug concentration was about 200 min in both the 0.4 mg and 0.8 mg groups (range 90-360 min). The plasma drug concentrations in the 0.8 mg group were approximately twice those in the 0.4 mg group; the ratio of the relative systemic availabilities was similarly 1.8:1. The absolute systemic availability was estimated at about 55% for both groups. Uptake of buprenorphine from the sublingual site was essentially complete by 5 h after the dose was given. 4 The implications for the timing of sublingual doses in clinical use are discussed.

Aged↗

'Getting up from here': frail older women's experiences after falling.

Few researchers have explored older persons' experiences of falling. As part of a descriptive phenomenological study of older widows' experience of home care, 25 interviews were conducted with nine frail women who had fallen at least once at home. Some women were able to get up on their own or tried to do so. For them, the phenomenon of "getting up from here" and its component phenomena, such as "finding something solid [on which to pull up]," were primarily focused on maximizing the opportunities afforded by the home's environmental features. When the women needed help to get up, the phenomenon of "getting up from here" was understood as an exemplar of the home care experience; the women's intentions were focused on contacting or interacting with people who were already assisting them as they lived alone at home. Understanding the variability in the experience of falling is an essential basis both for sensitive interaction with elders who have fallen and for appropriate assessment of frail elders who are at risk of falling in their homes.

Accidental Falls↗

Older widows' intention to keep the generations separate.

As the population ages, increasing numbers of older persons face decisions related to their living arrangements. In predictive studies of coresidence of older parents and their adult children, scholars have not studied older persons' preferred living arrangements. To consider the intentions of 16 older widows with regard to their future situations, a descriptive phenomenological investigation was conducted. The phenomenon "keeping the generations separate" is presented with its two components: continuing to live alone at home and avoiding being a burden to the children. Considered in the contexts of their experience of living alone at home and the life-world, "keeping the generations separate" is a source of insight about influences on older widows' preferences for future living arrangements.

Activities of Daily Living↗