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Biomedical subjects

E J Feuerman

Publications and source records attributed to E J Feuerman.

At least 91 records · Page 5Linked to original sources
PubMed1982

Generalised pustular psoriasis, psoriatic arthritis and nephrotic syndrome associated with systemic amyloidosis.

The case report is presented of a psoriatic patient with arthropathy, generalised pustular psoriasis and nephrotic syndrome, in whom systemic amyloidosis developed. The literature reports 13 cases of psoriasis associated with amyloidosis, 3 of whom suffered from pustular psoriasis as does our case. With the addition of our case, 12 of these 14 had concomitant arthropathy. This seems to suggest that arthritis is an important factor in the appearance of amyloidosis. Rectal biopsy and/or renal biopsy may be helpful in establishing the diagnosis of amyloidosis relatively early in patients with psoriatic arthritis.

Amyloidosis↗
PubMed1982

[Incontinentia pigmenti achromians (systematized depigmented nevus)].

Two girls of 1 1/2 und 4 years age and described with linear, arch-like depigementations which appeared in early childhood. In both children no additional abnormalities could be found. The problem of terminology is briefly discussed, and it is proposed to interpret this syndrome as a variant of a systematized naevus depigmentosus. There seems to be no justification for turning this clinical entity into a new syndrome, when the only clinical signs are the characteristic depigmentations without any additional abnormalities.

Child, Preschool↗
PubMed1981

The high incidence of Tinea pedis and unguium in patients with Kaposi's sarcoma.

Forty patients suffering from Kaposi's sarcoma (31 males, a females aged from 18 to 80 years) were examined for the presence of mycotic invasion of the toe-webs, toe-nails and soles. Fungi were found without exception in all patients. In 35 patients all three sites were invaded; the remaining 5 showed no involvement of the toe-nails. The causative agent was T. rubrum in 31 patients. T. mentagrophytes in 7, E. floccosum in 2. Four subjects with T. rubrum infection also showed a super-imposed C. albicans infection in the toe-webs. The skin tests with Trichophytin and Candidin yielded a mildly positive response to the former antigen in 4 cases and to the latter in 8 cases. The strikingly high percentage of affected cases in this group of patients with Kaposi's sarcoma is discussed.

Adolescent↗
PubMed1981

Atypical cases of Microsporum canis infection in the adult.

Eleven adult patients (7 males, 4 females) were found to be infected with Microsporum canis. There was involvement of the scalp in three patients: in one male and one female there were kerion-like lesions and in one male the lesions resembled seborrheic dermatitis. There were three cases of tinea barbae, males aged 28, 65 and 82 years, in the first resembling an infected single lesion of granuloma annulare, the second with a kerion-like lesion and the third with an abscess-like tumor. There were five patients with lesions in glabrous areas: one male with a lesion of the palm resembling erythema multiforme and one with an infection of the auricular lobe resembling a seborrheic dermatitis or otitis externa; of three females with tinea faciei one had a lesion simulating granuloma faciale, one simulating lymphocytic infiltration and one simulating discoid lupus erythematosus. A cat was the source of infection in three cases; in the remainder it could not be determined with certainty. It is of note that a continuous increase in infection with M. canis has been observed in Israel during the past five years.

Adult↗
PubMed1981

Dialysis therapy for psoriasis. Report of three cases and review of the literature.

Three patients with psoriasis, who were resistant to all modes of accepted therapy, underwent 32 hours of peritoneal dialysis weekly for ten weeks. In two patients, there was a clearing of 80% of the psoriatic lesions after completion of therapy. In one of these patients, there was a recurrence of the lesions two months later, but the other patient is still in relative remission after 12 months. The third patient had clearing of 50% of the lesions, but there was recurrence two months after cessation of treatment. This experience as well as a review of the literature indicates that dialysis may have a positive effect on psoriasis and that the effect obtained is more prominent with peritoneal dialysis than with hemodialysis.

Adult↗
PubMed1981

HLA antigens in Jews with pemphigus vulgaris.

The association of HLA antigens with pemphigus in Jewish patients of various ethnic origins was investigated. Of 45 Ashkenazi patients, 31 (68.6%) had A26 (p less than 10(-5) and 32 (7175) had BW38 ( less than 10(-5)0. Among the 11 non-Ashkenazi patients, 7 (63.6%) had A26 and only 1 had BW38. The question whether the antigen A26 or BW38 is linked with the disease is discussed. Our findings may suggest that the primary association of pemphigus is with A26. This association may be stronger in Jewish male patients than in females. In view of the recent literature and our results it may be presumed that pemphigus in Jews is associated with antigens of Loci A and DR. No differences between pemphigus vulgaris and pemphigus erythematosus were observed.

Adult↗
PubMed1981

Blood hyperviscosity in psoriasis.

A study of platelet function and whole-blood viscosity in 11 patients with the confirmed diagnosis of psoriasis revealed a significant elevation in whole-blood viscosity (3.33 +/- 0.37 cP) as compared with that found in a control group (2.80 +/- 0.1 cP). The platelet count and platelet aggregation with ADP, epinephrine and collagen as well as platelet malonyldialdehyde were all within the normal range in all the patients. It is suggested that the increased blood viscosity may contribute to the higher incidence of occlusive vascular disease occurring in patients with psoriasis.

Adenosine Diphosphate↗
PubMed1981

Acne with acute systemic reaction (acne fulminans?). Report of a case.

A 17-year-old girl, hospitalized because of severe cystic acne of six weeks' duration, developed symptoms of systemic disease, with fever, accelerated erythrocyte sedimentation rate, leukocytosis, thrombocytosis, arthralgia and anemia. Extensive investigation ruled out other possible causes for the systemic involvement, and there was a prompt response to steroid therapy. This case had features similar to those associated with "acute, febrile, ulcerative conglobate acne with poly-arthralgia," except that there was an absence of ulcerative lesions: nonetheless, the dominant picture was that of cystic involvement. We believe that the use of the term "acne fulminans" for this and similar cases would be appropriate.

Acne Vulgaris↗
PubMed1981

Cell-mediated immunity in patients with less than pemphigus vulgaris greater than before, during and after prolonged treatment with steroids.

A study was made of the number of T lymphocytes and thier functional activity in 16 patients with pemphigus vulgaris, 5 with involvement of the mucosa, 3 with involvement of the skin and 8 with involvement of both; 2 patients had been suffering from the disease for 7 years, one for one year and the remainder for one to 6 months prior to this investigation. Patients were tested prior to institution of treatment, while receiving initially high doses of steroids and subsequently on maintenance doses. T lymphocyte number was determined by the E rosette technique and their functional activity by a local xenogeneic graft-versus-host reaction (GVHR) developed in our laboratories. Prior to therapy 50% of the patients showed impairment in T cell function, with no improvement during intensive steroid therapy; subsequently, when the disease was under control, there was a clear tendency for function to return to normal. There was no correlation between duration of the disease and immune competence but there appeared to be a partial correlation between the latter and the degree of involvement. Our study indicates that long-term steroid therapy not only benefits the clinical condition of the patient but is associated with an improvement in the immunological status.

Adult↗