Biomedical subjects
Publications and source records attributed to E J Fairbanks.
A thin, large area transparent transmission chamber mounted below the accessory tray is described and its suitability for daily treatment delivery consistency is investigated. The sensitivity of the detector to changes in monitor unit setting, field size, wedge size, missing blocks, and wedges is presented. Some of the other potential applications are also discussed.
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Off-resonance spin locking is investigated as a low power method for achieving low field spin-lattice relaxation contrast using high field clinical MR imaging systems (e.g., 1.5 tesla). Spin-lattice relaxation times and equilibrium magnetizations in the off-resonance rotating frame (T1 rho(off), beta) were measured for tissue-mimicking phantom materials as a function of the ratio of the amplitude to the resonance offset of the spin-locking pulse (f1/delta). The phantom materials consisted of vegetable oil to simulate fat and two different gels containing 2% and 4% agar to simulate nonfatty tissues with different macromolecular compositions. These measurements were used to verify a signal strength equation for a multislice off-resonance spin-locking technique implemented on a clinical MR imaging system operating at 1.5 tesla. Although the oil showed little change in image contrast with increasing f1/delta, the two gels demonstrated a strong variation which provided improved discrimination compared to T1-weighted imaging. Off-resonance spin locking is suggested as a method for improving delineation of breast lesions and a preliminary clinical example from a patient volunteer is presented.
LiF:Mg,Ti thermoluminescent dosimeters (TLD's) were obtained from three manufacturers with the specification that they all lie within +/- 5% of the mean. All were chips of size 3 mm x 3 mm x 1 mm. The three sample groups were compared on the basis of their energy response, linearity of the thermoluminescent (TL) response with increasing exposure, sensitivity, and reproducibility of TL response. All TLD groups showed similar characteristics in energy response and linearity. This is to be expected since the base material and dopants were the same. However, the sensitivity varied among the three groups by as much as 40% and reproducibility measurements gave standard deviations ranging from 7% to 14% among the groups. Annealing procedures were identical in all cases, as were irradiation and readout conditions.