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Biomedical subjects

E I Suslov

Publications and source records attributed to E I Suslov.

36 records · Page 2Linked to original sources

[Vitamin E and its structural analogs in tuberculosis].

Efficiency of tocopherol, its analog with a shortened side chain as well as their quinons for tuberculosis was determined. All the studied compounds inhibited peroxide-formation processes in the liver homogenate and mitochondria. The vitamin E amount in the blood is considerably decreased in case of tuberculosis. The studied analogs increased its content and possessed a weak tuberculostatic but expressed antiedemic and antiinflammatory action. Administration of vitamin E in combination with isoniazid to sick animals had a favourable effect on the processes of tissue respiration and oxidative phosphorylation. If taking a sum of characters, tocopherol acetate with a shortened side chain is the most efficient of all the analogs under study for the tuberculosis therapy.

Animals↗

[Screening for malignant neoplasms by using the new method of marker diagnosis, the Oncotest].

The proposed method for tumor screening ("Oncotest") is based on detecting substances (calcium-histone complexes) in the human blood which are markers of malignant neoplasia. Using "Oncotest" in a series of 5411 cases, we identified malignant tumors of various histogenesis (cancer, sarcoma) arising in different sites in 69 cases. "Oncotest" is especially important for early (pre-clinical) detection of malignant neoplasms during preventive population screenings.

Biomarkers, Tumor↗