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Biomedical subjects

E Hemminki

Publications and source records attributed to E Hemminki.

At least 55 records · Page 3Linked to original sources

Impact of prenatal screening on maternity services--Finnish physicians' opinions.

BACKGROUND: The purpose of this survey was to find out whether Finnish physicians had thought about or had observed resource or organizational effects due to the offering of prenatal screening. METHODS: A mailed questionnaire survey sent in 1996-1997 in Finland to all leading Finnish obstetrician-gynecologists, to a random sample of obstetrician-gynecologists providing prenatal care, to general practitioners providing maternity care, and to other general practitioners. The number of respondents was 322 (response rate 70%). RESULTS: Most physicians supported the screening programs currently in wide use in Finland (serum screening for Down's syndrome and ultrasound for malformations), and over a third wanted to introduce the two genetic carrier screenings asked about. Most thought Down's screening took up resources, but they did not consider this to be important. The impact of screening on public or customer images of prenatal care was not an important issue. Instead, a diversity of opinions was expressed on whether the increasing numbers of prenatal screenings require organizational changes in current prenatal care provided within primary care, or whether a shift to hospital clinics is necessary to achieve more specialized care. CONCLUSIONS: Most physicians were not concerned by the potential organizational and resource implications of prenatal screening, and apparently they judge screening more from a health and individual patient point of view.

Abnormalities, Multiple↗

Accidental out-of-hospital births in Finland: incidence and geographical distribution 1963-1995.

BACKGROUND: The study aims to describe the incidence and geographical distribution of accidental out-of-hospital births (accidental births) in Finland in relation to the changes in the hospital network, and to compare the perinatal outcomes of accidental births and all hospital births. METHODS: Data for the incidence and distribution analyses of accidental births were obtained from the official statistics between 1962 and 1973 and from the national Medical Birth Registry (MBR) in 1992-1993. The infant outcomes were analyzed for the MBR data in 1991-1995. RESULTS: Between 1963 and 1975 the central hospital network expanded and by 1975 they covered 72% of births. The number of small maternity units has decreased since 1963. The incidence of accidental births decreased between 1963 and 1973, from 1.3 to 0.4 per 1000 births, and rose by the 1990s to 1/1000. In the 1990s the parity adjusted risk of an accidental birth was higher for residents of northern than of southern Finland, OR 2.51 (CI 1.75-3.60), and for residents of rural compared to urban municipalities, OR 3.26 (CI 2.48-4.27). The birthweight adjusted risk for a perinatal death was higher in accidental births than in hospital births, OR 3.11 (CI 1.42-6.84). CONCLUSIONS: A temporal correlation between closing of small hospitals and an increase in accidental birth rates was detected. Due to the poor infant outcomes of accidental births, centralization policies should include measures to their prevention.

Adult↗

Variation in referring newborns to special care in Finland.

We studied the frequency of referring newborns to special care in Finland and its variation between hospitals. Data was obtained from the nationwide Finnish Birth Register for 1991 and 1994. Newborns who during their first week of life had been in special care, in another hospital, in a respirator, or who had received a blood exchange were defined as having been in special care. This applied to 7% of newborns in 1991 and to 8% in 1994. The proportions of newborns in special care varied notably between hospitals of the same level. The differences could be explained by varying patient mixtures and different thresholds for referral to care. The indications for referring newborns into special care, especially in hospitals with high rates of referral, requires scrutiny.

Catchment Area, Health↗

Acceptance of screening and abortion for Down syndrome among Finnish midwives and public health nurses.

In this study we evaluated how well maternal serum screening and abortions for Down syndrome were accepted among midwives and public health nurses, and compared how those who accepted and did not accept abortions for Down syndrome differed from each other. The questionnaire was mailed in 1998 to 400 midwives and 400 public health nurses. 79 per cent responded. The majority said that all pregnant women should be offered a screening test for Down syndrome, but less than half accepted abortion for Down syndrome. Thus, the 'informative part' of the screening (serum screening itself) is supported more often than the 'operative part' (selective abortion)-or at least the 'operative part' was found to be a more difficult question. We suggest that whereas screening may be perceived as a question of more choices, information and self-determination, abortion is more clearly a moral question. The professional background characteristics and attitudes of those accepting and not accepting abortion for Down syndrome were relatively similar, but having a midwife's education, practical involvement in serum screening and having patients with Down syndrome were associated with a somewhat higher percentage of acceptance and a lower percentage of 'don't know' responses.

Abortion, Induced↗

Treatment of miscarriage: current practice and rationale.

OBJECTIVE: To describe health service use during miscarriage and medical treatment of miscarriage in Finland and the rationales behind them. METHODS: Description of the treatment practices was based on a survey sent to a nationally representative sample of 3000 Finnish women age 18-44 years in 1994, on national hospital care register data from 1988 and 1995, and on treatment recommendations in textbooks (from 1950-1994) for physicians, nurses, and midwives. Published, controlled studies that were identified through various systematic searches were reviewed for scientific evidence justifying the identified practices. RESULTS: According to the survey, 97% of the 326 women who had a miscarriage had visited a physician, and 74% were treated as inpatients. The hospital registers indicated that most (at least 84% in 1988, and 88% in 1995) women who had a miscarriage had their uteri evacuated operatively. According to the textbook recommendation, care by a physician, inpatient care, and routine uterine evacuations were seen as norms. No controlled studies providing empirical support for these practices were found. In general, studies were few and recent, and they placed emphasis on different evacuation methods. CONCLUSION: Current treatment of miscarriage is not based on controlled studies. All aspects of care, from best care provider to various interventions, urgently need further evaluation by trials.

Abortion, Incomplete↗

Women's decision-making in prenatal screening.

With serum screening (MS-AFP and hCG testing for Down's syndrome) women have to make several decisions in a limited time: whether to participate in the screening in the first place; then, if increased risk for fetal abnormality is detected, whether to have a diagnostic test, and finally, what to do if fetal abnormality is detected. The aim of this study was to examine how women themselves in an unselected population describe their decision-making in the different phases of serum screening. Women receiving a positive result from serum screening in two Finnish towns from September 1993 to March 1994 and a group of individually matched controls were invited to semistructured interviews; 45 index and 46 control women (79% of those invited) participated between their 29th and 37th weeks of gestation (mean 31 weeks). Although serum screening was most often presented as voluntary or as an option, half the women described participation as a routine or self-evident act; only one-fourth of the women described actively deciding about participation. After a positive screening result, women's reactions to diagnostic tests, and their intentions if disability would be detected, varied greatly. Most of the women actively decided about having diagnostic tests, but for 23% participation in diagnostic testing was called a self-evident act. Women's intentions regarding abortion varied from a firm decision to abort to a firm decision not to abort, and many remained ambivalent. Prenatal screening, which demands the making of several decisions in a limited time and is offered to all pregnant women as part of established maternity care, is not based on every participant's active decision-making and thus creates an ethical problem. This problem should receive special attention from those who develop, introduce and decide on new health care practices.

Abortion, Eugenic↗

Social class differences in health until the age of seven years among the Finnish 1987 birth cohort.

Studies on social class differences in childhood health are controversial partly because of different data collection methods, limited sample sizes and the use of limited numbers of health indicators. The increasing collection of health register data enables the use of such data in social class studies. Our purpose was to investigate social class differences in mortality and morbidity among all children born in Finland in 1987 (N=59,865 liveborns) until the age of seven by using several national health registers, and to study whether perinatal health explains these differences. The follow-up was based on data linkage with six national health registers, with 18 regional registers of mentally disabled children, covering the whole country, and with 38 educational registers of the largest county. Morbidity was measured in terms of a cumulative disease index, the cumulative incidence of asthma, diabetes, epilepsy and intellectual disability, hospitalisations, disease-related welfare benefits and special education. Social class, divided in four groups (I-III, Others) was defined by using the mother's occupation at the time the child was seven years old. Our study showed that register-based data collection is a feasible method for studying social class differences in health. In the unadjusted analysis, social class differences were found for all indicators except mortality after the age of one year and for the cumulative incidence of asthma and diabetes. After adjusting for confounders, the children in the lowest social class had the highest risk for poor health outcome both in the perinatal period and in childhood, and had the most intellectual disabilities, the highest mean of hospitalisation days, and received the most special education. The differences were not explained by perinatal health. The health of the children in the lowest social class was poorer, especially regarding mental indicators.

Chi-Square Distribution↗

Declining perinatal mortality in Finland between 1987 and 1994: contribution of different subgroups.

OBJECTIVE: To examine the extent to which the decline in perinatal mortality is attributable to some subgroups, especially to certain birthweight or gestation groups. STUDY DESIGN: A register study using the Finnish Medical Birth Register for years 1987 to 1994. RESULTS: Of the overall reduction in perinatal mortality from 8.8 to 6.7 per 1000 births, 78% was due to stillbirths, compared with 22% due to early neonatal deaths. The decline in mortality among infants who weighed under 1500 g at birth was the major contributor (62%) to the overall reduction in perinatal mortality. The largest decline in mortality in the stillbirth group occurred among those weighing < 1000 g, while for early neonatal deaths the group most affected weighed 1000-1499 g. A similar pattern emerged when the gestation-week groups were examined. CONCLUSION: The decline in perinatal mortality is attributable to stillbirths of very low birthweight. The most likely explanations for this result are the improved antenatal and neonatal care and the wider use of malformation screening.

Abortion, Spontaneous↗

Finnish physicians' attitudes towards preconsultation information: menopausal treatment practices as an example.

The purpose of this study was to investigate Finnish physicians' attitudes towards consumer groups provision of information about physicians' treatment practices, using menopause as a specific example. A questionnaire to be used to make a public brochure listing physicians by their menopausal and postmenopausal treatment practice was sent by consumer organizations to 812 physicians [gynecologists and general practitioners (GPs)] in 1995, after contacting the physicians' associations for support for this activity. The gynecological association had a negative attitude towards the study while that of the GPs' association was more favorable. The response rate was 38% (n = 307). Only 5% of the physicians who got the questionnaire wanted to participate in the planned brochure and only 21% of those responding considered preconsultation information a good idea. The most common reasons for not wanting to participate were that preconsultation information is medically unfeasible and that it would be incompatible with physician's current working practice. Approaches other than public brochures about physicians' treatment patterns are needed if we want to increase patients' participation in decision-making.

Adult↗

Health registers as a feasible means of measuring health status in childhood--a 7-year follow-up of the 1987 Finnish birth cohort.

Follow-up studies on health have usually been based on ad hoc cohort studies in which detailed information is collected specifically for research purposes on a certain group of people. The increasing collection of routine health data provides an alternative method of gathering follow-up data. In this study, the feasibility of using routinely collected health-register data and data linkages to follow up children's health was investigated. Five nationwide registers, 18 regional registers of intellectually disabled children and school administration data in one county were found to be of use for our follow-up and were combined with the 1987 Finnish Medical Birth Register (n = 60,254 births). In the follow-up, 62 children were untraced (0.1%), 327 were stillborn (0.5%), 440 died after birth (0.7%) and 287 emigrated (0.5%) before the age of 7 years. The cumulative incidences for all diseases (8.9% of all children living in Finland at the age of 7 years), for diabetes (3.0/1000), for epilepsy (6.8/1000) and for asthma (34.2/1000) correspond to the estimates of other studies, but our estimate for intellectual disabilities (18.0/1000, of whom 18% were reported to have an IQ of 70 or less) seems to be an underestimate. Our data collection did not provide reliable information on institutionalised children or children taken into care. Data collection conducted by using health registers is a feasible method, and it saves both time and financial resources compared with cohort studies. Potential problems with data linkage studies are variation in the content of data and in data quality of different registers and data protection issues.

Adolescent↗

The role of gynaecologists in women's health care--women's views.

OBJECTIVE: Reproductive matters are common reasons to use health services, and both primary care providers (general practitioners and public health nurses) and specialists (gynaecologists) can be consulted. The purpose of this study was to find out how Finnish women think about and use specialist care in reproductive matters; gynaecological health checks, contraception, and prenatal care served as examples. METHODS: The data come from a questionnaire survey sent in 1994 to a representative sample (74% response rate) of 18-44-year-old Finnish women (n=2189). RESULTS: Most (87%) women considered regular health checks by a gynaecologist important, and 55% had visited a gynaecologist regularly in the past 5 years. Healthier women and women having more education were more likely to visit gynaecologists regularly. Most women (86%) preferred a gynaecologist to a general practitioner for contraceptive matters, and 54% reported visiting one for their last contraceptive visit. Maternity centres with their public health nurses and general practitioners were the main source of prenatal care. CONCLUSIONS: The results suggest the need to study the benefits of regular gynaecological health checks, and to define the best provider in common reproductive matters. Evaluation should include organizational impacts, such as those of the division of work between primary and secondary health care and small area population responsibility.

Adolescent↗

Contraceptive health risks--women's perceptions.

The aim was to study women's concerns about health risks associated with contraceptives, in particular oral contraceptives and intrauterine devices (IUDs), and to investigate what factors are related to these concerns. A questionnaire was sent to a random sample of 3000 women aged 18-44 years in Finland in 1994. After two reminders, the response rate was 74% (n = 2189). Logistical models were used to examine factors that were related to concerns over oral contraceptives and IUDs. Half (n = 1096) of the respondents had at some time been concerned about the risks of contraceptives. Most concerns (71%) were related to oral contraceptives. Cardiovascular effects, cancer, infertility, mood changes and weight gain were the most commonly specified risks related to oral contraceptives, and infections, effects on menstruation and ectopic pregnancy were most mentioned regarding IUDs. Concerns about oral contraceptives were related to higher education [odds ratio (OR) 1.75; 95% confidence interval (CI) 1.38-2.21], past experience with the method (OR 1.81; 95% CI 1.45-2.26) and to a good knowledge about contraception and fertility (OR 1.68; 95% CI 1.29-2.19). Concern over IUD risks were most strongly related to past use of the method (OR 3.11; 95% CI 2.24-4.32) and higher age (35-44 years old, OR 2.99; 95% CI 1.52-5.87). Unlike women concerned about the risks of oral contraceptives, women with concerns about IUDs had had abortions more often than other women (OR 1.79; 95% CI 1.28-2.48). Women with concerns about oral contraceptives or IUDs used condoms or sterilization as their current contraceptive method significantly more often than other women. Results showed that concern about the risks of contraceptives is strongly related to women's past contraceptive experiences and influences their current use of contraceptives. More attention should be paid to information provided by health care professionals, especially that regarding risk probabilities.

Adolescent↗

Quality of care in abortion services in Finland.

BACKGROUND: The aim of this study was to describe the quality of abortion services and women's experiences with the care they had received during their abortion. METHODS: A population-based postal survey of 3000 randomly selected 18-44-year old Finnish women in 1994. The response rate was 74% (n=2189). The following were used as indicators of quality of services: referral problems, loss of follow up, adequacy of counseling, and satisfaction with treatment. RESULTS: Fifteen percent (n=320) of the respondents had experienced at least one abortion. After adjusting for age, women who had an abortion were more likely to come from the lower social class, to be divorced, widowed, or in a nonmarital relationship, and to have had previous pregnancies. Fifty-two percent reported not using any contraceptive method when getting pregnant. Altogether 6% reported referral problems and 8% did not have post-abortion follow-up. Twenty-five percent would have preferred more discussion with a physician or a nurse before the abortion and 30% after it. Psychological effects of abortion was the most often mentioned subject upon which they needed discussion. The need for discussion was not influenced by the length of time lapsed since the abortion. The satisfaction with treatment increased from 69% (abortion >10 years ago) to 82% (abortion <5 years ago). Dissatisfaction was related to need for more discussion and the abortion having been performed in a central hospital. CONCLUSION: The overall quality of abortion care was good but there is still a need for improvement, especially in the communication and human part of the care.

Abortion, Legal↗

On what grounds do women participate in prenatal screening?

Along with the rapid biomedical development of prenatal screening tests, target groups' attitudes and decision-making about, and the acceptance of, screening procedures have come into focus. To understand users' decision-making, it is essential to understand users' knowledge and perceptions of a procedure. The aim of this study was to examine Finnish women's knowledge and perceptions of, and stated reasons to participate in, two prenatal screening tests: serum screening and mid-trimester ultrasound screening. Subjects (n=1035) for the serum screening survey were catered for in the maternity care centres of two Finnish towns, where serum screening is available for all pregnant women. After one reminder, 88 per cent returned the questionnaire. Subjects (n=497) for the mid-trimester ultrasound screening survey were catered for in the obstetrical and gynaecological outpatient clinic of the city hospital of another town; the response rate was 85 per cent. Women's perceptions of the studied prenatal screening tests, serum screening and mid-trimester ultrasound screening, differed significantly, even though both are used to detect fetal malformations. Serum screening was far more often perceived to be connected with finding diseases or abnormalities than ultrasound screening. Another interesting finding was that the stated reasons for screening in general and the subjective reasons for participation were different. Reassurance was the personal reason most often mentioned in both the serum screening and the ultrasound group. Almost all women had the most superficial knowledge about serum screening; they knew whether it had been offered and that it is done to screen for Down syndrome. The greatest gaps in knowledge concerned the sensitivity of serum screening, its use in screening for congenital nephrosis, and diagnostic tests and their risks. Knowledge was poorer among women without a high school education. When counselling women about prenatal screening tests, more emphasis should be given to the sensitivity of serum screening, all of its screening uses, and the possible diagnostic tests and their risks. The fact that ultrasound screening can detect conditions which may lead to the possibility of a selective abortion should also be explained more fully.

Amniocentesis↗

Interest in alternative birth settings in Finland.

BACKGROUND: The aim of this study was to examine the extent of wishes for and realised choices of alternative and conventional birth care in Finland based on survey and registry data. METHODS: A population-based national survey to 3000 women of reproductive age and 400 men aged 18-24 and 40-44 in Finland and a cross-sectional analysis of all childbirths in 1990 1995 based on the National Medical Birth Registry (n=390, 943). RESULTS: In the survey 69% of women and 66% of men chose conventional hospital birth as their preferred alternative. An early discharge birth was chosen by 14% of women and 18% of men and home birth by 6% of women and 3% of men. Childless respondents were more likely than parents to choose an alternative other than conventional hospital birth, yet 16% of mothers and 14% of fathers would choose either home birth or early discharge from hospital in a future birth. The expressed interest in alternatives to conventional hospital care was far greater than what occurs in reality: in the MBR data 99% of births were conventional hospital births, 0.01% were planned homebirths and 0.9 % early discharge births. CONCLUSIONS: The study shows a discrepancy between expressed interests and actually realised choices of birth settings. The majority of female and male survey respondents would choose conventional hospital care for birth. However, the fact that even some women who had earlier birth experience preferred some form of alternative to the conventional hospital birth should be taken as a sign of women wanting choices in birth care.

Adult↗

Impact of postmenopausal hormone therapy on cardiovascular events and cancer: pooled data from clinical trials.

OBJECTIVE: To examine the incidence of cardiovascular diseases and cancer from published clinical trials that studied other outcomes of postmenopausal hormone therapy as some surveys have suggested that it may decrease the incidence of cardiovascular diseases and increase the incidence of hormone dependent cancers. DESIGN: Trials that compared hormone therapy with placebo, no therapy, or vitamins and minerals in comparable groups of postmenopausal women and reported cardiovascular or cancer outcomes were searched from the literature. SUBJECTS: 22 trials with 4124 women were identified. In each group, the numbers of women with cardiovascular and cancer events were summed and divided by the numbers of women originally allocated to the groups. RESULTS: Data on cardiovascular events and cancer were usually given incidentally, either as a reason for dropping out of a study or in a list of adverse effects. The calculated odds ratios for women taking hormones versus those not taking hormones was 1.39 (95% confidence interval 0.48 to 3.95) for cardiovascular events without pulmonary embolus and deep vein thrombosis and 1.64 (0.55 to 4.18) with them. It is unlikely that such results would have occurred if the true odds ratio were 0.7 or less. For cancers, the numbers of reported events were too low for a useful conclusion. CONCLUSIONS: The results of these pooled data do not support the notion that postmenopausal hormone therapy prevents cardiovascular events.

Cardiovascular Diseases↗

Knowledge and use of hormonal emergency contraception in Finland.

We studied the knowledge and use of hormonal emergency contraception (EC) in Finland by mailing a questionnaire to a national sample of 3000 women aged 18-44 years (response rate 74%). Ten percent of the women aged under 25 and 4% of all respondents had sometimes used EC. Unmarried women were more likely to report having used hormonal EC than were married women, and nulliparous women reported more use than did parous women. However, no statistically significant difference in EC use among women with or without previous abortion history was observed. Older women were less aware of EC than of other methods; only one-third of the women aged over 35 knew about this method. Current contraceptive practices were otherwise similar among ever-users and never-users of EC, but EC users more commonly reported using condom together with oral contraceptives or IUD. Nobody reported using EC as her only contraceptive method. Our findings suggest that EC is appropriately used in Finland, but more information about use of the method is still needed.

Abortion, Induced↗