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Biomedical subjects

E Heid

Publications and source records attributed to E Heid.

At least 127 records · Page 7Linked to original sources
PubMed1980

Ultrastructure of early pigmentary changes in Dowling-Degos' disease.

Dowling-Degos' anomaly is characterized by a reticular and spotted pigmentation of the skin folds; this pigmentary disturbance, occurring most often in women, is a dominant inherited genodermatosis which worsens progressively and may exhibit in the early phase rapid changes in severity after emotional stress. In a 9-year-old girl, an electonmicroscopic study of pigmented lesions showed a strong melanocytic activity with quantitative increase of the melanosomes; the average size of the melanosomes was not different when compared to normal Caucasoid skin, but in the keratinocytes they were distributed according to a dispersed pattern as in black skin. The pigmentary state of Dowling-Degos' disease is another example of melanocyte-keratinocyte interaction where the epidermal melanin pattern and the size of pigment granules are not in striking correlation. An accelerated rate of melanogenesis and pigmentation may be another factor determining a non-aggregated distribution of the melanosomes within the keratinocytes. The nature of the stimulus of pigmentation in these skin areas which are not sun-exposed is still unclear.

Child↗
PubMed1978

[Pityrosporum folliculitis (author's transl)].

Pityrosporum folliculitis occurs mainly among adult males on the back and may result from antibiotic and steroid administration. The lipophilic yeasts are numerous in the papulo-pustular lesions and can easily be demonstrated in the perifollicular inflammation on histological slides. 8 new cases with typical clinicopathological features are recorded by the authors. The best results are obtained with topically applied amphotericin B or econazol.

Adult↗
PubMed1978

[Keratosis follicularis spinulosa decalvans and amino-aciduria (author's transl)].

A new case of keratosis follicularis spinulosa decalvans (Siemens, 1925) in a 12 1/2 year old boy is related. This X-dominant inherited disturbance of follicular keratinization is associated with an amino-aciduria in the propositus and his mother, especially an increase of aspartic acid in urin and blood. The scarring infundibular plugs are constituted by nucleated keratin, which brightened up in polarized light and seems to be of internal trichilemmal origin.

Aspartic Acid↗
PubMed1977

[The action of levamisole on thymodependent rosettes in normal and atopic subjects].

Thymo-derived E-rosettes and fast E-rosettes have been determined in 26 normal and 17 atopic patients. The effect of levamisole in vitro has been studied by adjunction in the cell suspension at a concentration of 100 gamma/ml. In normal and atopic subjects the E-rosettes are not modified by levamisole. Fast E-rosettes are significantly increased by levamisole in normal but not in atopic patients. These results support the hypothesis of a functional deficiency of T-lymphocytes in atopy; they are correlated by the failure of treatment of atopic dermatitis by levamisole.

Dermatitis, Atopic↗
PubMed1977

[Serum IgE levels in scabies. Study about 100 cases].

IgE levels were determinated in 100 cases of human scabies. In 85 cases, the values are normal (mean value =160 UI/ml, 2 S.D.=528). In 15 cases with raised values, an associated disease (cirrhosis, atopic dermatitis) was always found. The results were compared with those of other authors.

Humans↗
PubMed1976

[Lymphocyte transformation test in Gell's and Coombs' drug reactions].

A method of interpretation of the lymphocyte transformation test is described which results on the basis of statistical evaluation. With this method good results were received in cases of drug induced side effects of type I according to Gell and Coombs. The investigations on 61 patients have shown that differneces between the clinical findings and lymphocyte transformation tests are rare. They are mainly in relation to false-positive reactions of the lymphocyte transformation test in Penicillin allergy.

Diagnostic Errors↗