Enzymatic hydrolysis of 2',3'-cyclic CMP by homohistidine-12-ribonuclease S'.
Explore the source record for details and available documents.
Cytosine Nucleotides↗
Biomedical subjects
E Havinga
Publications and source records attributed to E Havinga.
The role of the imidazolyl nitrogen atoms of histidine-12 in ribonuclease S.
S-peptide (residues 1--14) analogues in which the active histidine-12 residue is replaced by Npi-methyl-L-histidine, Ntau-methyl-L-histidine and beta-(pyrid-3-yl)-L-alanine were synthesized and tested for their capacity to bind to S-protein and to activate it. The results show that both imidazolyl nitrogen atoms are required for optimal catalytic functioning, Ntau being essential to the catalytic reaction itself, Npi playing a role in keeping the imidazole ring in the correct position.
Catalysis↗
Synthesis and enzymatic activity of an RNase S' analogue in which the 4-imidazolylglycyl residue takes the position and the role of histidine-12.
Explore the source record for details and available documents.
Animals↗
Studies on polypeptides.
Explore the source record for details and available documents.
Amino Acid Sequence↗
Vitamin D, example and challenge.
Explore the source record for details and available documents.
Alkenes↗
Studies on vitamin D and related compounds XX. The conformation of tachysterol; N. O. E. and 220 MHz N. M. R.
Explore the source record for details and available documents.
Chemical Phenomena↗
Some recent results in the chemistry and stereochemistry of vitamin D and its isomers.
Explore the source record for details and available documents.
Chemical Phenomena↗