Search PubMed⌕ Search

Biomedical subjects

E Harju

Publications and source records attributed to E Harju.

83 records · Page 5Linked to original sources
PubMedDate not supplied

Clinical features of Crohn's disease: a clinical study of one hundred patients found in an unselected population.

One hundred patients (mean age 34 years, range from 12 to 70 years) were treated at Tampere University Hospital during the thirteen year period, 1972-1984. Our hospital takes responsibility for the treatment of patients with Crohn's disease found in an unselected population of 400,000 inhabitants. In 73% of cases Crohn's disease was diagnosed before the age of forty. The mean interval between the first clinical signs and the diagnosis was 3.3 years. In 57% of the patients the diagnosis was reached within one year. In nine patients the primary diagnosis was colitis ulcerosa. Most patient were anemic and were in the state of inflammation and/or catabolism suggested by low blood hemoglobin concentration and high ESR and CRP values on admission. Three percent of the patients had macroscopic Crohn's disease in all parts of the gastrointestinal tract, whereas 22% had it only in the small intestine and 18% only in the colon. Fifty of the hundred patients had lesions in the terminal ileum and 20% in the anus. The specific finding for the present series was a high frequency of rectal lesions, in 29% of the patients. Histologically the condition was more often (P less than 0.001) revealed by the laparatomy specimen than the endoscopic biopsy, which gave a positive histology more often (P less than 0.001) in the lower than in the upper gastrointestinal tract. No gastrointestinal malignancies were found.

Adolescent↗
PubMedDate not supplied

The treatment of high enterocutaneous fistula with surgical drainage and total parenteral nutrition.

High enterocutaneous fistulas occurred in 17 malnourished patients after abdominal surgery, performed in most cases for serious primary disease, and were treated with emergency surgical drainage, in 15 cases, early resuturation, in six patients, and total parenteral nutrition (12.6 MJ) in all cases. No elective reconstructions were carried out. The fistulas healed in 27 +/- 20 days, except in three patients, with carcinoma of the stomach or necrosis of the pancreas, who died in sepsis.

Adult↗
PubMedDate not supplied

Dietary habits and eating related symptoms in out-patients following total gastrectomy and Roux-en-Y reconstruction for carcinoma of the stomach.

Dietary habits and eating related symptoms were studied by one week recording method in thirteen successive out-patients attending the routine control following total gastrectomy and Roux-en-Y reconstruction for carcinoma of the stomach. All the patients except one had daily eating related symptoms such as difficulties in swallowing or/and rapid filling of the stomach, or/and discomfort, meteorism and pain, or/and nausea, faintness, sweating and rapid pulse. The number of daily meals was high (eight to fifteen) and the amounts of food eaten small, consisting of one sandwich, or one fruit, or one glass of milk, especially in those patients with most symptoms and most frequent meals. The daily intake of energy (7.4 +/- 2.0 and 6.8 +/- 1.5 MJ in the males and females, respectively) and nutrients was low, and there were no differences between the daily energy intakes by the patients with eight or fifteen daily meals. Thus, it is concluded that in the out-patients following total gastrectomy and Roux-en-Y reconstruction for carcinoma of the stomach, the symptoms related to eating are common and frequent, what causes the high number of daily meals and decreases the quality of life of the patients. The meals of the patients are simple and the patients are prone to a reduced nutritional state due to the low intake of energy and nutrients.

Aged↗
PubMedDate not supplied

The effects of gastric surgery on serum ferritin concentrations.

Changes in serum ferritin concentrations were monitored for three months after gastric operation, in 25 patients. In 23 patients, the serum ferritin concentration was seen to be increased, one week postoperatively, as compared with the preoperative level. Thereafter, in most patients, the serum ferritin concentration gradually decreased to the initial preoperative level. Preoperatively, 13 of the total 25 patients had low serum ferritin concentrations, indicating depleted iron stores. In eleven of these patients, the serum ferritin concentrations followed the above-mentioned course and normal values of serum ferritin concentration were seen postoperatively, indicating normal body iron stores. In six of the ten patients with normal preoperative serum ferritin concentrations, there was a temporary increase within the limits of the normal range. The temporary postoperative increase of serum ferritin concentration was more marked in the patients who underwent total or partial gastrectomy than highly selective vagotomy or fundoplication. We conclude that measurement of serum ferritin concentration may give a false impression of normal body iron stores in the postoperative state.

Adult↗