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Biomedical subjects

E Harburg

Publications and source records attributed to E Harburg.

At least 37 records · Page 2Linked to original sources

Twelve blood markers and measures of temperament.

This project tested the association of 12 blood marker systems with the Eysenck Extraversion-Introversion/Neuroticism forms and the Buss-Plomin Temperament forms. The sample was about 400 males and 470 females who were given medical examinations during the Tecumseh Community Health Study (Michigan). ANOVA and Scheffe tests were used to test for significant differences; personality traits were adjusted for age. The Lewis red blood cell phenotypes were significantly associated with Anger and Impulsivity for males and Sensation-seeking (a subscale of Impulsivity) for females. It is suggested that these temperament factors merit further exploration.

Blood Group Antigens↗

Handedness and drinking-smoking types.

This work showed that more sinestrals both smoke and drink together more and abstain less in both uses than dextrals. This association is stronger for females than men, regardless of age. The sample included whites, 18 to 69 yr. old, who were residents of Tecumseh, Michigan (N = 1,153).

Adolescent↗

Parity and blood pressure among four race-stress groups of females in Detroit.

Blood pressures (BPs) of 755 Detroit, Michigan, area females have been analyzed in relation to parity, race and residential stress. Mean BP values have been adjusted by standard methods of covariance analysis for differing effects of age and body size among various groups being compared. Adjusted systolic and diastolic BPs are found to be significantly different for black and white females. A residential stress effect is also seen for systolic BP among white females. However, none of the regression relationships between BP and parity is found to be significant in the race-stress groups included in the study. Thus, neither the consideration of race and stress nor adjustments for age and body size appear to add new information to the complex subject of BP as it relates to childbearing.

Adult↗

Community norms of alcohol usage and blood pressure: Tecumseh, Michigan.

This research examines the relationship between alcohol usage and blood pressure in the adult population of a small community in Michigan. Findings suggest that blood pressure varies with alcohol usage linearly for men with a slight dip at 1-2 drinks per week, and curvilinearly for women with a low point at about 4 drinks per week. A method to measure public norms of alcohol intake and categories of drinking habits is presented. This technique may be useful in constructing drinking categories applicable in a community for both education and therapy.

Adolescent↗

Resentful and reflective coping with arbitrary authority and blood pressure: Detroit.

Two hypotheses about coping with an arbitrary authority, an angry boss, were tested: (1) styles of handling anger vary with social status, and (2) these styles are in turn related to blood pressure levels. Two styles of coping were tested: model R-R, Resentful vs. Reflective, and model I/O/R, Anger-In, Anger-Out, and Reflective. Handling an angry boss by Reflection is reported by more women than men, by those in middle-class areas rather than lower class, and does not vary by race. Working class report more use of Anger-Out than middle class who in turn report more use of Reflection. In general, the Anger-In response did not vary by race, sex, or area of residence (12-18%). For model R-R, Reflection of boss's anger was related to lower blood pressure when compared to Resentful responses, within sex, race, and residence groups. For model I/O/R, working-class, high stress persons who expressed Anger-Out showed the highest mean levels. Reflection is an appraisal response related to vascular and neural deceleration in stress experiments. This mode can be learned, and may aid in handling daily emotional-loaded stimuli to control blood pressure, along with learning a relaxation response.

Adaptation, Psychological↗

Skin color, ethnicity, and blood pressure I: Detroit blacks.

Census areas in Detroit were ranked for their stress scores based on instability (e.g., crime, marital break up) and socioeconomic status. Four areas were selected for detailed study: 1) high stress, population predominantly black, 2) white, 3) low stress, population predominantly black, 4) white. A sample was drawn from each area of persons of the predominant race, 25-60 years old, married and living with spouse, and having relatives in the Detroit Area. Nurses interviewed such persons; three blood pressure readings were taken during the first half-hour of medical history, and skin color was rated. Results show that darker skin color, for black males especially, is related to higher pressure, independently of nine control variables (e.g., age, weight, socioeconomic status, etc.). However, younger black males (25-39 years of age) in high stress areas had higher pressure than counterparts in low stress areas, regardless of skin color and relative weight; for older black males (40-59 years of age) darker skin color was correlated with higher pressure, regardless of relative weight or stress area. For 35 blacks whose fathers were from the West Indies, pressures were higher than those with American-born fathers. These findings suggest that varied gene mixtures may be related to blood pressure levels and that skin color, an indicator of possible metabolic significance, combines with socially induced stress to induce higher blood pressures in lower class American blacks.

Adult↗

Skin color, ethnicity, and blood pressure II: Detroit whites.

Census areas in Detroit were ranked for their stress scores based on instability (e.g., crime, marital break up) and socioeconomic status. Four areas were selected for detailed study: 1) high stress, population predominantly black and 2) white, and 3) low stress, population predominantly black and 4) white. A sample was drawn from each area of persons of the predominant race, 25-60 years old, married and living with spouse, and having relatives in the Detroit Area. Nurses interviewed such persons; three blood pressure readings were taken during the first half-hour of medical history, and skin color was rated. While lighter skin color showed a negligible relation to higher blood pressure, a four-category division of European national background based on a skin color cline in Europe from Northern areas to the Mediterranean was significantly associated with a nurse-rating of skin color. The rank order of this four category variable, white ethnicity, was related linearly to both systolic and diastolic blood pressure means. Respondents with parents from Mediterranean countries had the lowest pressures and those from Northern Europe had the highest. The relationship is stronger for women than men. The relationship was independent of nine other control variables including age, overweight, smoking etc., and high and low stress areas, although of greater magnitude for the high than low stress groups. In this article, findings in whites are compared with prior results in blacks. Findings suggest that physiological and biological correlates exist that can be explored profitably by future research.

Adult↗

Handedness and smoking.

This article reports the observation that proportionately more left-handed persons smoke than dextrals, and a greater proportion of left-handers than right-handers smoke 10 or more cigarettes daily, regardless of sex, race, stress of residence (or social class), and prior history of smoking. This association is especially strong among males and persons residing in residence areas of high stress (low income, low education), and weak among black females and persons who smoke 30 or more cigarettes daily. The sample was drawn from four census areas in Detroit differing by race, socioeconomic levels, and crime rates. Respondents and their spouses were 25 to 60 yr. old, married, and had relatives in the metropolitan area (N = 1496).

Adult↗

Mild high-renin essential hypertension. Neurogenic human hypertension?

To determine whether the elevated plasma renin activity in some cases of mild essential hypertension expresses sympathetic-nervous-system over-activity, we compared indexes of sympathetic activity in 16 patients with mild high-renin essential hypertension, 15 hypertensive patients with normal plasma renin activity and 20 normal subjects. Patients with elevated activity exhibited a raised plasma norepinephrine concentration (P less than 0.05), a greater fall in cardiac output with cardiac beta-adrenergic blockade by intravenous propranolol (P less than 0.01), reduction in total peripheral vascular resistance with alpha-adrenergic blockade produced by intravenous phentolamine (P less than 0.01), and reduction to normal of blood pressure by "total" autonomic blockade (atropine, propranolol and phentolamine). On psychometric testing, patients with high-renin hypertension, but not those with normal plasma renin activity, exhibited suppressed hostility (P less than 0.01), a behavioral pattern linked to increased sympathetic activity. The hypertension in these patients with high renin activity is neurogenic and possibly psychosomatic in origin.

Adolescent↗