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Biomedical subjects

E Haller

Publications and source records attributed to E Haller.

39 records · Page 3Linked to original sources
PubMed1978

[Frequency of drug prescriptions and their adverse effects in a medical department].

The enquiries carried out in our unit since 1971, in some 1600 patients who received in all more than 13000 drug prescriptions and who were observed during 3 periods whose total duration was 12 months, prompt the following conclusions. The number of adverse reactions in which the relationship of cause and effect with one or several drugs was either definite or probable amounted to 217, 2--3% among patients at admission and 5--11% of patients during their hospital stay. The average number of prescriptions per patient remained stable and the average number of drug reactions per 100 prescriptions varied from 0.6 to 1.6. Severe drug reactions occurred in 1.1% of patients at admission and 1.1% of patients during their hospital stay.

Drug Prescriptions↗
PubMed1975

[Factors that intervene in adverse drug reactions].

Drug prescriptions and adverse reactions occurring during 2 periods of 3 months in a department of medicine were analyzed by computer programs. Among 148 reactions suspected, 130 were considered definite or probable by one physician (1.6 reaction per 100 drug prescriptions). The patients who suffered from an adverse reaction were older, were hospitalized for a longer period of time and received more drugs than the others. The data were submitted to two physicians who were asked to determine the degree of probability of each reaction independently. There were many discrepancies between physicians' judgements (52% of the reactions) if one of them had a brief summary of the case history and the other had all the data available. The discrepancies were far fewer (18.1%) if both physicians had all the data available, and were due to the drug(s) suspected (8.8%) or to the influence of the disease (9.3%).

Age Factors↗